Eukaryotic Transcription Factors
Seiten
2007
|
5th edition
Academic Press Inc (Verlag)
978-0-12-373983-4 (ISBN)
Academic Press Inc (Verlag)
978-0-12-373983-4 (ISBN)
Provides coverage of the developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. This book also covers: the potential of transcription factors as therapeutic targets in human disease; importance of histone modifications; and transcriptional elongation.
Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events.
Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events.
DNA sequences, transcription factors and chromatin structureMethods for studying transcription factorsRNA polymerases and the basal transcriptional complexFamilies of DNA binding transcription factorsActivation of gene expression by transcription factorsRepression of gene expression by transcription factorsRegulation of transcription factor synthesisRegulation of transcription factor activityTranscription factors and human disease
| Erscheint lt. Verlag | 12.9.2007 |
|---|---|
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 175 x 244 mm |
| Gewicht | 1180 g |
| Themenwelt | Wirtschaft ► Betriebswirtschaft / Management ► Marketing / Vertrieb |
| ISBN-10 | 0-12-373983-7 / 0123739837 |
| ISBN-13 | 978-0-12-373983-4 / 9780123739834 |
| Zustand | Neuware |
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