Corynebacterium glutamicum

Biology and Biotechnology

Masayuki Inui, Koichi Toyoda (Herausgeber)

Buch | Hardcover

VIII, 378 Seiten

2020 | 2nd ed. 2020
Springer International Publishing (Verlag)
978-3-030-39266-6 (ISBN)

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This book shows how data from genome sequencing allows engineering of the entire cellular metabolism, and how systems biology permits further optimization of C. glutamicum as a biocatalyst. Covers gene regulation, biorefinery applications and more.

This updated second edition covers the molecular biology, genome engineering tools and comprehensive analysis techniques for Corynebacterium glutamicum. Aside from modern omics-based approaches, the authors also focus on cell physiology, including cell division, central carbon metabolic pathways, and the respiratory chain. Readers will learn how primary mechanisms like energy metabolism can be applied in processes like biorefinery. Newly added topics include cell envelope structures and aromatic compound metabolism in C. glutamicum. These chapters will be particularly useful for those interested in the microbial production of commodity chemicals, fuels, and proteins.

Corynebacteriacea are already some of the most important industrial microorganisms. Understanding the cell physiology of C. glutamicum will help manufacturers to increase their product range and productivity through efficient metabolic engineering.

Masayuki Inui Molecular Microbiology and Biotechnology

Part I. Characteristics of Corynebacterium glutamicum.- Chromosome Organization and Cell Growth of Corynebacterium glutamicum.- Architecture and Biogenesis of the Cell Envelope of Corynebacterium glutamicum.- Respiratory Chain and Energy Metabolism of Corynebacterium glutamicum.- Part II. Regulation at Various Levels.- Sigma Factors of RNA Polymerase in Corynebacterium glutamicum.- Global Transcriptional Regulators Involved in Carbon, Nitrogen, Phosphorus, and Sulfur Metabolisms in Corynebacterium glutamicum.- Post-Translational Modifications in Corynebacterium glutamicum.- Part III. Amino Acids.- Recent Advances in Amino Acid Production.- Pathways at Work: Metabolic Flux Analysis of the Industrial Cell Factory Corynebacterium glutamicum.- Amino Acid Exporters in Corynebacterium glutamicum.- Part IV. Metabolic Design for a Wide Variety of Products.- Metabolic Engineering in Corynebacterium glutamicum.- Aromatic Compound Catabolism in Corynebacterium glutamicum.- Aromatic Compound Production by Corynebacterium glutamicum.

Erscheinungsdatum	15.04.2020
Reihe/Serie	Microbiology Monographs
Zusatzinfo	VIII, 378 p. 74 illus., 34 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	746 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Technik ► Umwelttechnik / Biotechnologie
Schlagworte	Amino Acids • Aromatic Compounds Metabolism • Bioalcohol • bioplastic • Corynebacterium glutamicum • Metabolic Engineering • Metabolome • Post-translational regulation • Protein Secretion • transcriptional regulation
ISBN-10	3-030-39266-X / 303039266X
ISBN-13	978-3-030-39266-6 / 9783030392666
Zustand	Neuware