Principles of Protein X-ray Crystallography
Seiten
1999
|
2nd Revised edition
Springer-Verlag New York Inc.
978-0-387-98587-9 (ISBN)
Springer-Verlag New York Inc.
978-0-387-98587-9 (ISBN)
- Titel erscheint in neuer Auflage
- Artikel merken
Protein crystallography is vital to research in biophysics, biochemistry/molecular biology, and drug development. Part of the "Springer Advanced Texts in Chemistry" series, this book provides an introduction to the principles of the field.
X-ray crystallography has been a vital method for studying the structure of proteins and other macromolecules for many years. As the importance of proteins continues to grow in a wide range of research fields from basic biochemistry and biophysics to pharmaceutical development and biotechnology, more and more researchers have found a knowledge of X-ray diffraction to be an indispensable tool. Professor Drenth, recognized internationally for his numerous contributions to crystallographic research, has provided a technically rigorous introduction to the subject. This book provides the theoretical background necessary to understand how the structure of proteins is determined at atomic resolution. It is intended to be an introduction for graduate students, postdoctoral researchers, and established scientists who want to apply protein crystallography in their own endeavors, or need to understand the subject in order to critically evaluate the literature. "Principles of Protein X-ray Crystallography" is appropriate as a textbook for courses in biochemistry and biophysics, including protein structure and function, structural biology, and macromolecular structure.
X-ray crystallography has been a vital method for studying the structure of proteins and other macromolecules for many years. As the importance of proteins continues to grow in a wide range of research fields from basic biochemistry and biophysics to pharmaceutical development and biotechnology, more and more researchers have found a knowledge of X-ray diffraction to be an indispensable tool. Professor Drenth, recognized internationally for his numerous contributions to crystallographic research, has provided a technically rigorous introduction to the subject. This book provides the theoretical background necessary to understand how the structure of proteins is determined at atomic resolution. It is intended to be an introduction for graduate students, postdoctoral researchers, and established scientists who want to apply protein crystallography in their own endeavors, or need to understand the subject in order to critically evaluate the literature. "Principles of Protein X-ray Crystallography" is appropriate as a textbook for courses in biochemistry and biophysics, including protein structure and function, structural biology, and macromolecular structure.
Crystallizing a Protein X-ray Sources and Detectors Crystals The Theory of X-ray Diffraction by a Crystal Average Reflection Intensity and Distribution of Structure Factor Data Special Forms of the Structure Factor The Solution of the Phase Problem by the Isomorphous Replacement Method Phase Improvement Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Determination Molecular Replacement Direct Methods Laue Diffraction Refinement of the Model Structure The Combination of Phase Information Checking for Gross Errors and Estimating the Accuracy of the
| Reihe/Serie | Springer Advanced Texts in Chemistry |
|---|---|
| Zusatzinfo | 129 illus. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 156 x 234 mm |
| Gewicht | 687 g |
| Einbandart | gebunden |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Chemie ► Organische Chemie | |
| Naturwissenschaften ► Geowissenschaften ► Mineralogie / Paläontologie | |
| ISBN-10 | 0-387-98587-5 / 0387985875 |
| ISBN-13 | 978-0-387-98587-9 / 9780387985879 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
Mehr entdecken
aus dem Bereich
aus dem Bereich
