Epigenetics and Chromatin
Springer Berlin (Verlag)
978-3-540-23372-5 (ISBN)
Epigenetics refers to heritable patterns of gene expression which do not depend on alterations of genomic DNA sequence.
This book provides a state-of-the-art account of a few selected hot spots by scientists at the edge in this extremely active field. It puts special emphasis on two main streams of research. One is the role of post-translational modifications of proteins, mostly histones, on chromatin structure and accessibility. The other one deals with parental genomic imprinting, a process which allows to express a few selected genes from only one of the parental allele while extinguishing the other.
Chromatin Remodeling Factors and DNA Replication.- Epigenetic Inheritance of Chromatin States Mediated by Polycomb and Trithorax Group Proteins in Drosophila.- How to Pack the Genome for a Safe Trip.- Chromatin Modifications on the Inactive X Chromosome.- Chromatin Mechanisms in Drosophila Dosage Compensation.- DNA Methylation in Epigenetic Control of Gene Expression.- The Epigenetic Breakdown of Cancer Cells: From DNA Methylation to Histone Modifications.- Developmental Regulation of the ?-Globin Gene Locus.- Epigenetic Regulation of Mammalian Imprinted Genes: From Primary to Functional Imprints.- Seed Development and Genomic Imprinting in Plants.
From the reviews:
"This book contains ten excellent chapters ... . Thoroughly covers a rapidly developing and expanding field. The different chapters are well written and provide clear, concise and informative views on the topic. Notably, each chapter ends with a conclusion describing current models and future challenges in epigenetics. ... both the expert and the novice will find this book a valuable source of information on the various epigenetic phenomena." (Frank Sauer, Nature Cell Biology, Vol. 7 (10), October, 2005)
"Professor Philippe Jeanteur, who is one of the editors of this PMSB Springer series, coordinated a well reknown group of scientists working on epigenetics to provide us with an updated collection of papers treating epigenetic phenomena in Mammals, insects and plants. Well done: careful presentations, well illustrated and rich in bibliography, this book is a must for those interested in epigenetics." (Carlo Alberto Redi, European Journal of Histochemistry, Vol. 49 (4), 2005)
| Erscheint lt. Verlag | 10.1.2005 |
|---|---|
| Reihe/Serie | Progress in Molecular and Subcellular Biology |
| Zusatzinfo | XIII, 266 p. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 600 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Schlagworte | Allele • biochemistry • Cell Biology • Chromatin • DNA • DNA Replication • epigenetics • Epigenom • gene expression • genes • Human genetics • Post-translational modification • proteins • Translation |
| ISBN-10 | 3-540-23372-5 / 3540233725 |
| ISBN-13 | 978-3-540-23372-5 / 9783540233725 |
| Zustand | Neuware |
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