Applications in Forensic Proteomics

Protein Identification and Profiling

Buch | Hardcover

248 Seiten

2020
Oxford University Press Inc (Verlag)
978-0-8412-3649-3 (ISBN)

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This volume consists of "case studies" illustrating the invaluable use of proteomics as a tool in the life sciences.

Proteomics is a mature research tool in the life sciences, and it can be a powerful addition to the forensic science toolbox. This work presents several areas in which proteomics was used to answer forensic questions. Illustrating current applications of proteomic methods, this work introduces opportunities for proteomics to answer compelling questions in forensic science and biosecurity. These "case studies" will be valuable to both practicing forensic scientists
and researchers developing proteomics methods.

Eric D. Merkley earned a B.S. in biochemistry from Brigham Young University in 2003 and Ph.D. in biochemistry from the University of Washington in 2010. He completed post-doctoral studies in the well-known proteomics research group at Pacific Northwest National Laboratory (PNNL). In 2013, Dr. Merkley joined PNNL's Chemical and Biological Signature Sciences Group. Research interests include mass spectrometric analysis of biothreat agents and protein toxins, strengthening proteomics bioinformatics strategies to ensure readiness for forensic and legal applications, and developing standards for forensic applications of proteomics.

Chapter 1. Introduction to Forensic Proteomics, Eric D. Merkley
Chapter 2. A Proteomics Tutorial, Eric D. Merkley, Brooke L. D. Kaiser, and Helen Kreuzer
Chapter 3. Proteomic Sample Preparation Techniques: Toward Forensic Proteomic Applications, Carrie Nicora, Marina Gritsenko, Anna Lipton, Karen L. Wahl, and Kristin E. Burnum-Johnson
Chapter 4. NextGen Serology: Leveraging Mass Spectrometry for Protein-Based Human Body Fluid Identification, Heather E. McKiernan, Catherine O. Brown, Luciano Chaves Arantes, Phillip B. Danielson, and Kevin M. Legg
Chapter 5. Informatics Approaches to Forensic Body Fluid Identification by Proteomic Mass Spectrometry, Wenke Liu, Erin Butler, Heyi Yang, David Fenyo, and Donald Siegel
Chapter 6. Fingermarks as a New Proteomic Specimen: State of the Art and Perspective of In Situ Proteomics, Simona Francese and Cristina Russo
Chapter 7. Human Identification Using Genetically Variant Peptides in Biological Forensic Evidence, Fanny Chu, Katelyn E. Mason, Deon S. Anex, Phillip H. Paul, and Bradley R. Hart
Chapter 8. Proteomics in the Analysis of Forensic, Archaeological, and Paleontological Bone, Michael Buckley
Chapter 9. Proteomics for Microbial Forensics, Eric D. Merkley
Chapter 10. ISO 17025 Accreditation of Method-Based Mass Spectrometry for Bioforensic Analyses, Stephen R. Cendrowski and Alaine M. Garrett
Chapter 11. Unambiguous Identification of Ricin and Abrin with Advanced Mass Spectrometric, Assays Suzanne R. Kalb and Francois Becher
Chapter 12. Challenges in the Development of Reference Materials for Protein Toxins, R. Zeleny, A. Rummel, D. Jansson, and B. G. Dorner
Chapter 13. The Statistical Defensibility of Forensic Proteomics, Kristin H. Jarman and Eric D. Merkley

Editors' Biographies
Author Index
Subject Index

Erscheinungsdatum	10.07.2020
Reihe/Serie	ACS Symposium Series
Verlagsort	New York
Sprache	englisch
Maße	184 x 260 mm
Gewicht	778 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Chemie ► Analytische Chemie
	Recht / Steuern ► EU / Internationales Recht
	Recht / Steuern ► Strafrecht ► Kriminologie
ISBN-10	0-8412-3649-6 / 0841236496
ISBN-13	978-0-8412-3649-3 / 9780841236493
Zustand	Neuware