Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B

Buch | Hardcover

220 Seiten

2021
Academic Press Inc (Verlag)
978-0-12-824143-1 (ISBN)

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Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more.

David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid β-protein (Alzheimer's disease) and α-synuclein (Parkinson’s disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Co-Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.

Preface

David Teplow

1. Relevance of transgenic mouse models for Alzheimer's disease

Leon Tai, Juan Maldonado Weng, Mary Jo LaDu and Scott Brady

2. Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?

Abhisek Mukherjee, Andrea D Becerra Calixto, Melissa Chavez, Jean Paul Delgado Charris and Claudio Soto

3. Activity-dependent neuroprotective protein (ADNP)-end-binding protein (EB) interactions regulate microtubule dynamics toward protection against tauopathy

Yanina Ivashko-Pachima and Illana Gozes

4. Applying available knowledge and resources to alleviate familial and sporadic neurodegenerative disorders

Mark P. Mattson

5. The cellular machinery of post-endocytic APP trafficking in Alzheimer's disease: A future target for therapeutic intervention?

Lawrence S.B. Goldstein and Utpal Das

6. The search for novel targets in Alzheimer's disease—The 90s redux

Christian Behl

7. Adult hippocampal neurogenesis in Alzheimer's disease

Ahmed Disouky and Orly Lazarov

8. Early detection and personalized medicine: Future strategies against Alzheimer's disease

Antonio Di Meco and Robert Vassar

9. Inflammation and Parkinson’s disease pathogenesis: Mechanisms and therapeutic insight

Gianluigi Forloni, Pietro la Vitola, Milica Cerovic and Claudia Balducci

Erscheinungsdatum	19.01.2021
Reihe/Serie	Progress in Molecular Biology and Translational Science
Mitarbeit	Herausgeber (Serie): David B. Teplow
Verlagsort	San Diego
Sprache	englisch
Maße	152 x 229 mm
Gewicht	480 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-12-824143-8 / 0128241438
ISBN-13	978-0-12-824143-1 / 9780128241431
Zustand	Neuware