Protein Function Prediction

Methods and Protocols

Buch | Softcover

239 Seiten

2018 | Softcover reprint of the original 1st ed. 2017
Humana Press Inc. (Verlag)
978-1-4939-8368-1 (ISBN)

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This volume presents established bioinformatics tools and databases for function prediction of proteins. Reflecting the diversity of this active field in bioinformatics, the chapters in this book discuss a variety of tools and resources such as sequence-, structure-, systems-, and interaction-based function prediction methods, tools for functional analysis of metagenomics data, detecting moonlighting-proteins, sub-cellular localization prediction, and pathway and comparative genomics databases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step instructions of how to use software and web resources, use cases, and tips on troubleshooting and avoiding known pitfalls.

Thorough and cutting-edge, Protein Function Prediction: Methods and Protocols is a valuable and practical guide for using bioinformatics tools for investigating protein function

Using PFP and ESG Protein Function Prediction Web Servers.- GHOSTX: A Fast Sequence Homology Search Tool for Functional Annotation of Metagenomic Data.- From Gene Annotation to Function Prediction for Metagenomics.- An Agile Functional Analysis of Metagenomic Data using SUPER-FOCUS.- MPFit: Computational Tool for Predicting Moonlighting Proteins.- Predicting Secretory Proteins with SignalP.- The ProFunc Function Prediction Server.- G-LoSA for Prediction of Protein-Ligand Binding Sites and Structures.- Local Alignment of Ligand Binding Sites in Proteins for Polypharmacology and Drug Repositioning.- WATsite2.0 with PyMOL Plugin: Hydration Site Prediction and Visualization.- Enzyme Annotation and Metabolic Reconstruction Using KEGG.- Ortholog Identification and Comparative Analysis of Microbial Genomes using MBGD and RECOG.- Exploring Protein Function Using the Saccharomyces Genome Database.- Network-Based Gene Function Prediction in Mouse and Other Model Vertebrates using MouseNet Server.- The FANTOM5 Computation Ecosystem: Genomic Information Hub for Promoters and Active Enhancers.- Multi-Algorithm Particle Simulations with Spatiocyte.

Erscheinungsdatum	16.08.2018
Reihe/Serie	Methods in Molecular Biology ; 1611
Zusatzinfo	71 Illustrations, color; 11 Illustrations, black and white; X, 239 p. 82 illus., 71 illus. in color.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Bioinformatics • Gene Ontology • metagenomics data • Microbial Genome Database • moonlighting-proteins • MPFit • seb-cellular localization prediction • sequence-based function prediction methods • SignalP
ISBN-10	1-4939-8368-7 / 1493983687
ISBN-13	978-1-4939-8368-1 / 9781493983681
Zustand	Neuware