CRISPR

Advances in Research and Applications

Dr Xin Wang (Autor)

Buch | Softcover

160 Seiten

2017
Nova Science Publishers Inc (Verlag)
978-1-5361-2946-5 (ISBN)

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Genome editing using CRISPR has been identified as one breakthrough technology in recent research. Today, it is difficult to open a journal or a newspaper without reading about the application of CRISPR gene editing technology to basic research, public health, therapeutics or diagnostics. Although some problems of CRISPR remain to be solved, such as bio-safety and ethical issues, it may change peoples futures. This book is to meet the needs of basic molecular biochemists, pharmacologists, medical students, clinical practitioners and scientists, as well as a broad spectrum of readers who wish to understand the advances in research and applications of CRISPR. The contributing authors are basic scientists as well as students who major in biochemistry and pharmacology. The book presents the current research in the CRISPR model, focusing on its advances and applications. Topics discussed in this compilation include: Targeting of hepatic diseases using CRISPR; applications and advances of CRISPR in animal models; gene targeting on the Cyp2c Locus in rats via CRISPR; applications of CRISPR for therapy in human genetic diseases; utilization of CRISPR in gene function and drug target validation; applications of CRISPR in plant genome editing; and genome editing on human embryos using CRISPR.

Dr Xin Wang received his Ph.D. degree in pharmacology from the Chinese University of Hong Kong, and postdoctoral training in the University of Texas Medical Branch. He has been working in the East China Normal University as associate professor since 2011. His research fields include pharmacokinetics, integrative approach for the study of anticancer effects of Chinese medicinal (CM) herbs (chemical analysis, pharmacology, pharmacokinetics, adverse effect/toxicity, and quality control of CM herbs), and herb-drug interactions, in particular chemopreventive and synergistic anticancer effects of CM herbs in the combinational chemotherapy of anticancer drugs. Currently, Dr. Wang is hosting or participating in many projects supported by the Science and Technology Commission of Shanghai Municipality and the National Natural Science Foundation of China. Dr. Wang has published more than 30 SCI papers in international peer-reviewed journals and contributed four book chapters. Meanwhile, he is dedicated to social activities and serves as the editorial board member and ad-hoc reviewer of many SCI journals, such as Gene, Journal of Translational Medicine, Toxicology Research, Phytomedicine, Journal of Pharmaceutical and Biomedical Analysis, Journal of Pharmacy and Pharmacology, Phytotherapy Research, Biomedical Chromatography, European Journal of Histochemistry, and Fitoterapia et al.

Erscheinungsdatum	10.03.2018
Verlagsort	New York
Sprache	englisch
Maße	155 x 230 mm
Gewicht	320 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	1-5361-2946-1 / 1536129461
ISBN-13	978-1-5361-2946-5 / 9781536129465
Zustand	Neuware