Genomics of Pattern Recognition Receptors
Springer Basel (Verlag)
978-3-0348-0687-9 (ISBN)
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation.- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword.- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer.- Structural Genomic Variation in Other Toll-like Receptors and Cancer.- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer.- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer.- Structural Genomic Variation in NOD-Like Receptors and Cancer.- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases.- Hot Spots In the Field: Where Should We Go.
From the reviews:
"This book comprehensively covers the polymorphism of genes-encoding pattern recognition receptors (PRRs) ... . The book is intended for immunologists, cancer researchers, cardiologists, epidemiologists, microbiologists, and geneticists, as well as PhD, graduate, and undergraduate students of biomedical faculties and their lecturers. This is a unique book that analyzes the field of PRR genomics and its practical applications. ... This book will be quite useful for a very wide audience." (Omer Iqbal, Doody's Book Reviews, March, 2014)
| Erscheint lt. Verlag | 10.9.2013 |
|---|---|
| Zusatzinfo | XI, 185 p. |
| Verlagsort | Basel |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 467 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Schlagworte | Cancer • Cardiovascular Diseases • immune response • NOD-like receptors • Pathogen-associated patterns • receptors • Toll-like receptors |
| ISBN-10 | 3-0348-0687-6 / 3034806876 |
| ISBN-13 | 978-3-0348-0687-9 / 9783034806879 |
| Zustand | Neuware |
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