Protein Structure Prediction
Humana Press Inc. (Verlag)
978-0-89603-637-6 (ISBN)
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Protein Structure Prediction is aimed at the novice, as well as experienced researchers in this field who all need detailed information that combines theoretical and practical aspects. Its major intent is to include information relevant to the daily work of a research scientist, but may not always be obvious in the original scientific literature. Covers many aspects, from sequence analysis, which is often the starting point for algorithms, through secondary and tertiary methods, to the prediction of docked complexes, which are essential to fully understand biological function. Also covers the development of suitable folding potentials essential for many of the methods presented in the volume. Expert knowledge of protein structure prediction from the contributors is applied to many disciplines, such as the identification of domains and motifs; the comparative modeling of proteins; and ab initio approaches to protein loop, side chain, and protein prediction.
This is an essential resource to both the expert and non-expert in the field, as the need for accurate and useful predicted structures continues to increase due to advances in technology and the understanding of the principles of protein structure folding.
An Overview of Protein Structure Prediction; Multiple Sequence Alignment; Protein Structure Comparison; Discovering Patterns Conserved in Sets of Unaligned Protein Sequences; Identification of Domains From Protein Sequences; Prediction of Secondary Structure; Comparative Protein Structure Modeling: Introduction and Practical Examples with MODELLER; A Practical Guide to Protein Structure Prediction; Derivation and testing Residue-Residue Mean-Force Potentials for Use in Protein Structure Prediction; Genetic Algorithms and Protein Folding; Scoring Functions for Ab-initio Methods; Ab Initio Loop Modeling and Its Application to Homology Modeling; The Dead-End Elimination Theorem: Mathematical Aspects, Implementation, Optimisations, Evaluation and Performance; Classification of Protein Folds; Modeling Transmembrane Helix Bundles by Restrained MD Simulations; Predictive Models of Protein Active Sites; Flexible Docking of Peptide Ligands to Proteins; Geometrical Docking Algorithms: A Practical Approach; Protein-Protein Docking: Generation and Filtering of Complexes
| Reihe/Serie | Methods in Molecular Biology ; v. 143 |
|---|---|
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 153 x 229 mm |
| Gewicht | 699 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| ISBN-10 | 0-89603-637-5 / 0896036375 |
| ISBN-13 | 978-0-89603-637-6 / 9780896036376 |
| Zustand | Neuware |
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