Fast Facts: Comprehensive Genomic Profiling (eBook)

Making precision medicine possible

B.L. Rapoport, G. Troncone, F. Schmitt, S. Nayler (Autoren)

eBook Download: PDF | EPUB

2020
108 Seiten
S. Karger AG (Verlag)
978-3-318-06819-1 (ISBN)

Infos

Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy

Produkt-Details

• Erscheint lt. Verlag: 3.11.2020
• Verlagsort: Basel
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• ISBN-10: 3-318-06819-5 / 3318068195
• ISBN-13: 978-3-318-06819-1 / 9783318068191