Fast Facts: Comprehensive Genomic Profiling

Making Precision Medicine Possible

Bernardo L. Rapoport, Giancarlo Troncone, Fernando Schmitt, Simon Nayler (Autoren)

Buch | Softcover

108 Seiten

2020
Karger, S (Verlag)
978-3-318-06818-4 (ISBN)

Infos

Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: - Genetic mutations and biomarkers - Understanding next-generation sequencing - Elements of comprehensive genomic profiles - Role in precision oncology - Predictive and prognostic biomarkers - Overcoming barriers to genotype-directed therapy

Produkt-Details

• Erscheinungsdatum: 29.09.2020
• Zusatzinfo: 17 fig., 17 in color, 13 tab.
• Verlagsort: Basel
• Sprache: englisch
• Maße: 148 x 210 mm
• Gewicht: 200 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Schlagworte: Genetics
• ISBN-10: 3-318-06818-7 / 3318068187
• ISBN-13: 978-3-318-06818-4 / 9783318068184
• Zustand: Neuware