Regulation of Vitamin A Homeostasis by the Stellate Cell (Vitamin A-Storing Cell) System (eBook)

Mutsunori Fujiwara, Yoshihiro Mezaki, Mayako Morii, Haruki Senoo, Kiwamu Yoshikawa (Herausgeber)

eBook Download: PDF

2016
63 Seiten
Nova Science Publishers (Verlag)
978-1-61122-267-8 (ISBN)

Infos

Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis. In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesize a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins. Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts. This book discusses and presents research on vitamin A-storing cells.

Produkt-Details

• Erscheint lt. Verlag: 1.1.2017
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• ISBN-10: 1-61122-267-2 / 1611222672
• ISBN-13: 978-1-61122-267-8 / 9781611222678