Regulation of Vitamin A Homeostasis by the Stellate Cell (Vitamin A-Storing Cell) System
Seiten
2011
Nova Science Publishers Inc (Verlag)
978-1-61761-313-5 (ISBN)
Nova Science Publishers Inc (Verlag)
978-1-61761-313-5 (ISBN)
Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80 per cent of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. This book discusses and presents research on vitamin A-storing cells.
Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis. In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesise a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins. Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts. This book discusses and presents research on vitamin A-storing cells.
Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis. In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesise a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins. Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts. This book discusses and presents research on vitamin A-storing cells.
Introduction; Nuclear Receptors; Involvement in Hepatic Diseases; Stap/Ctyoglobin Expression In HSCS; Development (Ontogeny & Phylogeny); Ageing; Immunity & HSCS; Conclusions; Index.
| Verlagsort | New York |
|---|---|
| Sprache | englisch |
| Maße | 215 x 140 mm |
| Gewicht | 108 g |
| Themenwelt | Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| ISBN-10 | 1-61761-313-4 / 1617613134 |
| ISBN-13 | 978-1-61761-313-5 / 9781617613135 |
| Zustand | Neuware |
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