Total Synthesis of (±)-Maoecrystal V

Jianxian Gong (Autor)

Buch | Hardcover

XII, 137 Seiten

2014
Springer Berlin (Verlag)
978-3-642-54303-6 (ISBN)

Infos

In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.

Inhalt

Research Background for Natural Product Maoecrystal V and Its Family.- The Model Study of Natural Product Maoecrystal V.- The total synthesis study of Maoecrystal V.- Summary.

Produkt-Details

• Erscheint lt. Verlag: 10.3.2014
• Reihe/Serie: Springer Theses
• Zusatzinfo: XII, 137 p. 177 illus., 1 illus. in color.
• Verlagsort: Berlin
• Sprache: englisch
• Maße: 155 x 235 mm
• Gewicht: 397 g
• Themenwelt: Medizin / Pharmazie ► Pharmazie
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Naturwissenschaften ► Chemie ► Physikalische Chemie
• Schlagworte: Intramolecular Diels-Alder Reaction • Maoecrystal V • natural product • Pinhey Arylation • Stereoselective • Tetrahydrofuran Oxa-Bridge Skeleton • total synthesis • Wessely Oxidative Dearomatization
• ISBN-10: 3-642-54303-0 / 3642543030
• ISBN-13: 978-3-642-54303-6 / 9783642543036
• Zustand: Neuware