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Cadmium: From Toxicity to Essentiality

Astrid Sigel, Helmut Sigel, Roland KO Sigel (Herausgeber)

Buch | Hardcover

560 Seiten

2013
Springer (Verlag)
978-94-007-5178-1 (ISBN)

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Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted.

1. The Bioinorganic Chemistry of Cadmium in the Context of Its Toxicity. - 2. Biogeochemistry of Cadmium and Its Release to the Environment. - 3. Speciation of Cadmium in the Environment. - 4. Determination of Cadmium in Biological Samples. - 5. Imaging and Sensing of Cadmium in Cells. - 6. Use of 113Cd NMR to Probe the Native Metal Binding Sites in Metalloproteins: An Overview. - 7. Solid State Structures of Cadmium Complexes with Relevance for Biological Systems. - 8. Complex Formation of Cadmium(II) with Sugar Residues, Nucleobases, Phosphates, Nucleotides, and Nucleic Acids. - 9. Cadmium(II) Complexes of Amino Acids and Peptides. - 10. Natural and Artificial Proteins Containing Cadmium. - 11. Cadmium in Metallothioneins. - 12. Cadmium-Accumulating Plants. - 13. Cadmium Toxicity in Plants. - 14. Toxicology of Cadmium and Its Damage to Mammalian Organs. - 15. Cadmium and Cancer. - 16. Cadmium in Marine Phytoplankton.Natural and Artificial Proteins Containing Cadmium. - 11. Cadmium in Metallothioneins. - 12. Cadmium-Accumulating Plants. - 13. Cadmium Toxicity in Plants. - 14. Toxicology of Cadmium and Its Damage to Mammalian Organs. - 15. Cadmium and Cancer. - 16. Cadmium in Marine Phytoplankton.Cadmium and Cancer. - 16. Cadmium in Marine Phytoplankton.

“This is a fascinating book that provides an up-to-date review of the very relevant and timely problem of cadmium contamination and toxicity in the environment. … it will be greatly beneficial for graduate students working on cadmium ecotoxicology. … it will doubtlessly complement well the knowledge of many researchers and professors.” (Michel Lavoie, The Quarterly Review of Biology, Vol. 90 (2), June, 2015)“The 11th volume in the ‘Metals Ions in Life Sciences Series’ addresses one imminent challenge of the 21st century, namely the chronic low exposure to cadmium that occurs in a global setting mainly from dietary sources. … the audience for this volume will certainly be as broad and there will be lots of unknown and essential facts every reader can extract from this compendium. I strongly recommend to collect this volume for your private library.” (Nicolai Burzlaff, Inorganica Chimica Acta, Vol. 421, 2014)"The chapters in this book are written authoritatively, will stimulate further research in a variety of disciplines, and be widely consulted. This series is a must for bioinorganic chemists, for inorganic biochemists, and of course toxicologists and indeed all interested in the role of metals in biology"- Peter J Sadler, J. Inorg. Biochem. 129 (2013) 173"This volume follows the high standards set by its predecessors. Its detail and thoroughness make it an excellent resource for research workers already engaged in investigating the biological chemistry of cadmium, and those who may become interested in the subject. This reviewer gives it a strong recommendation"- John S. Thayer, Coord. Chem. Rev. 257 (2013) 3070

Erscheint lt. Verlag	8.3.2013
Reihe/Serie	Metal Ions in Life Sciences ; 11
Zusatzinfo	43 Illustrations, color; 72 Illustrations, black and white; XXXVI, 560 p. 115 illus., 43 illus. in color.
Verlagsort	Dordrecht
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Schulbuch / Wörterbuch
	Medizin / Pharmazie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Chemie ► Analytische Chemie
	Naturwissenschaften ► Chemie ► Anorganische Chemie
Schlagworte	cadmium and cancer • cadmium-nucleotide and -nucleic acid interactions • cadmium-protein interactions, metallothioneins • essentiality for marine phytoplankton • toxicology of Cd to mammals, microorganisms and plants
ISBN-10	94-007-5178-8 / 9400751788
ISBN-13	978-94-007-5178-1 / 9789400751781
Zustand	Neuware