International Review of Cytology (eBook)

A Survey of Cell Biology

Kwang W. Jeon (Herausgeber)

eBook Download: PDF

2004 | 1. Auflage
336 Seiten
Elsevier Science (Verlag)
978-0-08-049568-2 (ISBN)

Infos

International Review of Cytology presents current advances and comprehensive reviews in cell biology - both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address biosynthesis and alternate targeting of the lysosomal cysteine protesase cathepsin L; microtubule-associated proteins and their essential roles during mitosis; molecular and functional analysis of the dictyostelium centrosome; polytene chromosomes; and insect basic leucine zipper proteins and their role in cyclic AMP dependent regulation of gene expression.

Inhalt

Cover 1
Contents 6
Contributors 10
Chapter 1. Biosynthesis and Alternate Targeting of the Lysosomal Cysteine Protease Cathepsin L 12
I. Introduction 13
II. Biosynthesis of Procathepsin L 14
III. Biosynthetic Pathways 19
IV. Expression of Cathepsin L and Its Targeting 31
V. Fate of Procathepsin L Targeted to Endosomes 38
VI. Activity of Secreted Procathepsin L 45
VII. Concluding Remarks 49
References 51
Chapter 2. Microtubule-Associated Proteins and Their Essential Roles During Mitosis 64
I. Introduction 64
II. Mitotic Apparatus 78
III. MAPs Required for Cell Division: Identification and Properties 85
IV. Organization of the Mitotic Spindle 102
V. Microtubule–Kinetochore Attachment and Metaphase Chromosome Alignment 108
VI. Chromosome Segregation 120
VII. Mitotic Exit and Cytokinesis 122
VIII. Concluding Remarks 127
References 129
Chapter 3. Molecular and Functional Analysis of the Dictyostelium Centrosome 166
I. Introduction 167
II. Molecular Analysis of Centrosome Composition 172
III. Molecular and Functional Analysis of Centrosomal Proteins in Dictyostelium 177
IV. Microtubule-Associated Proteins as Integral Parts of the Centrosome 188
V. Conclusions and Perspectives 203
References 204
Chapter 4. Polytene Chromosomes: 70 Years of Genetic Research 214
I. Introduction 215
II. Organization of Polytene Chromosomes 217
III. Dosage Compensation 248
IV. Replication in Polytene Chromosomes 251
V. Heterochromatins 252
VI. Telomeres in Polytene Chromosomes 261
VII. Conclusion 264
References 265
Chapter 5. Insect Basic Leucine Zipper Proteins and Their Role in Cyclic AMP-Dependent Regulation of Gene Expression 288
I. Introduction 289
II. Basic Leucine Zipper Proteins 289
III. cAMP Response Element Binding (CREB) Proteins 297
IV. Concluding Remarks 310
References 311
Index 322

Produkt-Details

• Erscheint lt. Verlag: 7.12.2004
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zellbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Themenwelt: Technik
• ISBN-10: 0-08-049568-0 / 0080495680
• ISBN-13: 978-0-08-049568-2 / 9780080495682