Multiple Primary Malignancies (eBook)

Andrea Renda (Autor)

eBook Download: PDF

2009 | 2009
XXII, 290 Seiten
Springer Milan (Verlag)
978-88-470-1095-6 (ISBN)

Infos

In 2006, when my colleague Andrea Renda proposed multiple primary malignancies (MPM) as the subject of the Biennial Report to the 2008 Congress of the Italian - ciety of Surgery, I, together with the Steering Committee, quickly agreed. Recent progress in our understanding of the etiopathology of these neoplasms has led to - novative and significant progress on the clinical level. Importantly, the incidence of the onset of two or more tumors in the same patient suggests a more than casual - lationship. Furthermore, the occurrence of MPM derives from several different me- anisms-viral, iatrogenic, immunologic, environmental, and hereditary-such that any form of treatment must take into account the etiology of these tumors. After an epidemiological introduction, this monograph analyzes various aspects of multitumoral syndromes based on the experience of the Department of Surgical Sciences, along with that of other clinical departments of the University Federico II of Naples. In the discussion of inherited tumors, reference is made to the series of patients treated at the Department of Surgery at the University of Siena. The many topics that comprise this volume range from carcinogenesis to diagnostic strategies, and from epidemiology to innovations in imaging and endoscopic techniques. Among the clinical aspects, particular emphasis is given to sporadic and hereditary syndromes, as these patients are frequently treated by general surgery departments.

Inhalt

Foreword 6
Preface 7
Contents 8
Contributors 11
Chapter 1 Nosography 19
Chapter 2 Epidemiology: Data from Cancer Registries 25
Chapter 3 Bioinformatics in MPM: Using Decision Trees To Predict a Second Tumor Site 45
Chapter 4 Carcinogenesis 69
Chapter 5 Iatrogenic Second Tumors 80
Chapter 6 Immunodeficiency and Multiple Primary Malignancies 99
Chapter 7 Multiple Primary Malignancies and Human Papilloma Virus Infections 113
Chapter 8 The Hereditary Syndromes 122
Chapter 9 Multifocal and Multicentric Tumors 144
Chapter 10 The Cancer Spectrum Related to Hereditary and Familial Breast and Ovarian Cancers 158
Chapter 11 The Role of Genetic Predisposition and Environmental Factors in the Occurrence of Multiple Different Solid Tumors. The Experience of the University Hospital of Sienna 171
Chapter 12 “ Sporadic” Colorectal Tumors in Multiple Primary Malignancies 193
Chapter 13 Multiple Primary Malignancies: “Non-codified” Associations 209
Chapter 14 Laboratory for Patients at Risk of Multiple Primary Malignancies 225
Chapter 15 Multiple Primary Malignancies: Role of Advanced Endoscopy To Identify Synchronous and Metachronous Tumors of the Digestive Tract 235
Chapter 16 Diagnostic Imaging Techniques for Synchronous Multiple Tumors 245
Chapter 17 “ DNA- Guided” Therapy 259
Chapter 18 Chemoprevention 281
Conclusions 294
Subject Index 298

Produkt-Details

• Erscheint lt. Verlag: 11.2.2009
• Reihe/Serie: Updates in Surgery
• Reihe/Serie: Updates in Surgery
• Zusatzinfo: XXII, 290 p.
• Verlagsort: Milano
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Schlagworte: abdominal surgery • classification • Endoscopy • epidemiology • Genetic • Imaging • Imaging techniques • Surgery • therapy • tumour
• ISBN-10: 88-470-1095-0 / 8847010950
• ISBN-13: 978-88-470-1095-6 / 9788847010956