Mouse in Biomedical Research (eBook)

Normative Biology, Husbandry, and Models

Stephen Barthold, Muriel Davisson, James G. Fox, Christian E. Newcomer, Fred W. Quimby, Abigail Smith (Herausgeber)

eBook Download: EPUB

2006 | 2. Auflage
816 Seiten
Elsevier Science (Verlag)
978-0-08-046907-2 (ISBN)

Infos

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Inhalt

Front Cover 1
The Mouse in Biomedical Research: Normative Biology, Husbandry, and Models 4
Copyright Page 5
Table of Contents 6
List of Reviewers 11
List of Contributors 12
Foreword 15
Preface 16
Normative Biology 16
Chapter 1. Gross Anatomy 18
Chapter 2. Mouse Physiology 40
Chapter 3. Reproductive Biology of the Laboratory Mouse 108
Chapter 4. Endocrinology: Bone as a Target Tissue for Hormonal Regulation 140
Chapter 5. Hematology of the Laboratory Mouse 150
Chapter 6. Clinical Chemistry of the Laboratory Mouse 188
Management, Techniques, and Husbandry 188
Chapter 7. Gnotobiotics 234
Chapter 8. Management and Design: Breeding Facilities 252
Chapter 9. Design and Management of Research Facilities for Mice 288
Chapter 10. Nutrition 338
Chapter 11. Health Delivery and Quality Assurance Programs for Mice 402
Chapter 12. Environmental and Equipment Monitoring 426
Chapter 13. Biomethodology and Surgical Techniques 454
Chapter 14. In-Vivo Whole-Body Imaging of the Laboratory Mouse 506
Use of Mice in Biomedical Research 506
Chapter 15. Behavioral Testing 530
Chapter 16. Cardiovascular Disease: Mouse Models of Atherosclerosis 552
Chapter 17. Convulsive Disorders 582
Chapter 18. Eye Research 612
Chapter 19. Genetic Analysis of Rodent Obesity and Diabetes 634
Chapter 20. Mouse Models in Aging Research 654
Chapter 21. Mouse Models of Inherited Human Neurodegenerative Disease 690
Chapter 22. Mouse Skin Ectodermal Organs 708
Chapter 23. Quality Control Testing of Biologics 748
Index 776
Color Plate Section 810

Produkt-Details

• Erscheint lt. Verlag: 15.12.2006
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Themenwelt: Technik
• Themenwelt: Veterinärmedizin
• Themenwelt: Weitere Fachgebiete ► Land- / Forstwirtschaft / Fischerei
• ISBN-10: 0-08-046907-8 / 0080469078
• ISBN-13: 978-0-08-046907-2 / 9780080469072