Comparative Pharmacokinetics
Iowa State University Press (Verlag)
978-0-8138-2138-2 (ISBN)
- Titel ist leider vergriffen;
keine Neuauflage - Artikel merken
This book presents a unique, highly practical overview of pharmacokinetics. It explains the scientific data and mathematical models of the discipline within the context of biological reality. "Comparative Pharmacokinetics" uses a complete model of the field, from facts and constructs to clinical manifestations. Written for students, researchers, and comparative medicine clinicians, this book thoroughly explains and assesses both mechanistic, compartmental models, and the newer empirical noncompartmental models, considering strengths and weaknesses of each. "Comparative Pharmacokinetics" also explains establishment of appropriate parameters and proper collection and linking of data. Cross-referenced information provides multiple opportunities for study from a variety of perspectives and ultimately aids decision making. This book concludes with application of techniques to common problems.
Jim E. Riviere, D.V.M., Ph.D. is the Burroughs Wellcome Fund Distinguished Professor of Veterinary Pharmacology and Director, Center for Chemical Toxicology Research and Pharmacokinetics, Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, N.C. .
Introduction; Principles of drug movement in the body; Absorption; Distribution; Renal Elimination; Hepatic biotransformation and biliary excretion; Compartmental models; Noncompartmental models; Nonlinear models; Physiological models; Dosage regimens; Simultaneous pharmacokinetics-pharmacodynamics modeling; Study design and data analysis; Population pharmacokinetics models and Bayesian forecasting applied to clinical pharmacokinetics; Dosage adjustment in renal diseases; Interspecies extrapolations; Tissue residues and withdrawal times, Index.
| Erscheint lt. Verlag | 11.10.2003 |
|---|---|
| Verlagsort | Arnes, AI |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Gewicht | 585 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Veterinärmedizin | |
| ISBN-10 | 0-8138-2138-X / 081382138X |
| ISBN-13 | 978-0-8138-2138-2 / 9780813821382 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
