Natural Products Isolation
Humana Press Inc. (Verlag)
978-0-89603-362-7 (ISBN)
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Researchers from both industry and academia present in detail techniques for the extraction and isolation of natural products of all classes. These experienced experimentalists describe a wide array of methodologies, including basic chromatography, ion-exchange methods, HPLC, countercurrent and planar chromatography, SFE, and crystallization. They also address the specific problems involved in working with plants, marine organisms, water-soluble compounds, scale-up, dereplication and partial identification, and follow-up of a natural product lead. For the less-experienced they offer hands-on advice - using real examples - about how to approach an extraction in general, when and why to apply a particular technique, how to carry out the methods described, and how to modify conditions according to the compound being isolated.
How to Approach the Isolation of a Natural Product Richard J. P. Cannell. Initial Extraction and Product Capture F. Patrick Gailliot. Supercritical Fluid Methods Ed Venkat and Srinivas Kothandaraman. Isolation by Low-Pressure Column Chromatography Gino M. Salituro and Claude Dufresne. Isolation by Ion-Exchange Methods Claude Dufresne. Isolation by Preparative HPLC Paul Stead. Isolation by Planar Chromatography Simon Gibbons and Alexander I. Gray. Separation by High-Speed Countercurrent Chromatography James McAlpine. Crystallization and Final Stages of Purification Norman Shankland Alastair J. Florence and Richard J. P. Cannell. Dereplication and Partial Identification of Natural ProductsFrank VanMiddlesworth and Richard J. P. Cannell. Purification of Water-Soluble Natural Products Yuzuru Shimizu. Special Problems with the Extraction of Plants Gloria L. Silva Ik-Soo Lee and A. Douglas Kinghorn. Isolation of Marine Natural Products Amy E. Wright. Scale-Up of Natural Products Isolation Michael S. Verrall and Stephen R. C. Warr. Follow-Up of Natural Product Isolation Richard J. P. Cannell.
| Erscheint lt. Verlag | 1.1.1998 |
|---|---|
| Reihe/Serie | Methods in Molecular Biology |
| Verlagsort | Totowa, NJ |
| Sprache | englisch |
| Maße | 229 x 152 mm |
| Gewicht | 825 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Technik ► Umwelttechnik / Biotechnologie | |
| ISBN-10 | 0-89603-362-7 / 0896033627 |
| ISBN-13 | 978-0-89603-362-7 / 9780896033627 |
| Zustand | Neuware |
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