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Biology and Therapeutic Application of Mesenchymal Cells -

Biology and Therapeutic Application of Mesenchymal Cells (eBook)

Kerry Atkinson (Herausgeber)

eBook Download: EPUB
2016 | 1. Auflage
1048 Seiten
Wiley (Verlag)
978-1-118-90729-0 (ISBN)
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The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues.

  • Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications
  • Describes the therapeutic potential of mesenchymal stem and stromal cells in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models
  • Discusses the current status of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues
  • Written and edited by leaders in the field

The Biology and Therapeutic Application of Mesenchymal Cells is an invaluable resource for those studying stem cells, cell biology, genetics, gene or cell therapy, or regenerative medicine.



Kerry Atkinson, MBBS MD DTM&H FRCP FRACP, is an Adjunct Professor at the University of Queensland Centre for Clinical Research in Brisbane, Australia, an Adjunct Professor in the Stem Cell Laboratories, Queensland University of Technology at the Translational Research Institute, Brisbane, Queensland, Australia and a Specialist in Internal Medicine at the Salisbury Medical Centre, Brisbane, Queensland, Australia.
The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues. Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications Describes the therapeutic potential of mesenchymal stem and stromal cells in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models Discusses the current status of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues Written and edited by leaders in the field The Biology and Therapeutic Application of Mesenchymal Cells is an invaluable resource for those studying stem cells, cell biology, genetics, gene or cell therapy, or regenerative medicine.

Contributors


Anurag Agrawal, Centre of Excellence for Translational Research in Asthma & Lung Disease, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

Tanveer Ahmad, Centre of Excellence for Translational Research in Asthma & Lung Disease, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

Giulio Alessandri, Department of Cerebrovascular Diseases, Fondazione IRCCS Neurological Institute Carlo Besta, Milan, Italy

Chullikana Anoop, Stempeutics Research Pvt Ltd, Whitefield, Bangalore, India

Jesse D. Armitage, Centre for Asthma, Allergy and Respiratory Research, School of Medicine & Pharmacology; Stem Cell Unit, Institute of Respiratory Health; University of Western Australia, Nedlands, WA, Australia

Kerry Atkinson, The University of Queensland Centre for Clinical Research, Brisbane, Queensland, Australia; The Queensland University of Technology/Institute of Health and Biomedical Innovation at the Translational Research Centre, Brisbane, Queensland, Australia; Salisbury Medical Centre, Brisbane, Australia

Luigi Balducci, Medestea Research and Production Laboratories, Consorzio CARSO, Bari, Italy

Wayne Balkan, The Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA

Jennifer J. Bara, AO Research Institute Davos, Davos Platz, Switzerland

Frédéric Baron, Department of Hematology, Le Centre Hospitalier Universitaire of Liège and Unit of Hematology, University of Liège, Liège, Belgium

Frank Barry, Regenerative Medicine Institute, National University of Ireland Galway, Galway, Ireland

Etienne Baudoux, Laboratory of Cell and Gene Therapy (LTCG), Le Centre Hospitalier Universitaire of Liège and University of Liège, Liège, Belgium

Julie R. Beegle, The Institute for Regenerative Cures/Stem Cell Program, University of California, Davis, Sacramento, CA, USA

Yves Beguin, Department of Hematology; Laboratory of Cell and Gene Therapy (LTCG), Le Centre Hospitalier Universitaire of Liège and Unit of Hematology, University of Liège, Liège, Belgium

Y.A. Belyi, S.N. Fyodorov Eye Microsurgery Complex Kaluga Affiliate, Kaluga, Russia

Naveen K. Bhatraju, Centre of Excellence for Translational Research in Asthma & Lung Disease, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

Francisco J. Blanco, Proteomics Group-ProteoRed-PRB2/ISCIII, Rheumatology Division INIBIC-CHU A Coruña, Spain

Josephine Bodle, Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, USA

Siddaraju V. Boregowda, Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL, USA

Laura J. Bray, School of Biomedical Sciences, Institute of Health & Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; Queensland Eye Institute, South Brisbane, Australia; Leibniz Institute for Polymer Research Dresden, Max Bergmann Center of Biomaterials, Dresden, Germany

Jan E. Brinchmann, Norwegian Center for Stem Cell Research, Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway

Alexandra Briquet, Laboratory of Cell and Gene Therapy (LTCG), Le Centre Hospitalier Universitaire of Liège and University of Liège, Liège, Belgium

Annelies Bronckaers, Group of Morphology, Biomedical Research Institute (BIOMED), Hasselt University, Diepenbeek, Belgium

Gary Brooke, Reneuron, Guildford, Surrey, UK

Dimitrios Cakouros, Mesenchymal Stem Cell Laboratory, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, South Australia, Australia; Cancer Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia

Irene Calvo-Asensio, Biosciences, Newcastle Road, Dangan, National University of Ireland, Galway, Ireland

Rhodri Ceredig, Biosciences, Newcastle Road, Dangan, National University of Ireland, Galway, Ireland

Adisri Charoenpanich, Biology Department, Faculty of Science, Silpakorn University, Thailand

Lin Chen, Department of Oral and Maxillofacial Surgery, The Second Xiangya Hospital, Central South University, Changsha, Peoples Republic of China

Qing Chen, Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences/Shanghai Jiao Tong University School of Medicine, Shanghai, China

James A. Cornwell, Developmental and Stromal Cell Biology Division, Victor Chang Cardiac Research Institute; Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW, Australia

Sharon Natasha Cox, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy

A.T. Crane, Field Neurosciences Institute Laboratory for Restorative Neurology, Brain Research and Integrative Neuroscience Center, Program in Neuroscience, Central Michigan University, Mount Pleasant, MI

Brendan G. Cronin, Queensland Eye Institute, South Brisbane, Australia

Olivier Delloye, Laboratory of Cell and Gene Therapy (LTCG), Le Centre Hospitalier Universitaire of Liège and University of Liège, Liège, Belgium

Olivier Detry, Department of Abdominal Surgery and Transplantation, CHU of Liège and University of Liège, Liège, Belgium

Michael Doran, Queensland University of Technology/Institute of Health and Biomedical Innovation at the Translational Research Institute, Brisbane, Queensland, Australia

G.L. Dunbar, Field Neurosciences Institute Laboratory for Restorative Neurology, Brain Research and Integrative Neuroscience Center, Program in Neuroscience, Central Michigan University, Mount Pleasant, MI, USA; Field Neurosciences Institute, Saginaw, MI, USA

K. Jane Escott, Emerging Innovations Unit, Scientific Partnering and Alliances, AstraZeneca R&D, Cheshire, UK

Leah Etheridge, Department of Biology, University of York, York, UK

Fernando A. Fierro, The Institute for Regenerative Cures/Stem Cell Program, University of California, Davis, Sacramento, CA, USA

Leanne Foyn, School of Biomedical Sciences, Queensland University of Technology, Brisbane, Australia; Queensland Eye Institute, South Brisbane, Australia

Jacques Galipeau, Department of Hematology and Medical Oncology, Winship Cancer Institute, Atlanta, GA, USA

Caroline E. Gargett, Department of Obstetrics and Gynaecology, Monash University, Victoria, Australia; MIMR-PHI Institute of Medical Research, Clayton, Victoria, Australia

Tatyana Gavrilova, Albert Einstein College of Medicine and The Montefiore Medical Center, New York, NY, USA

Sean Gaynard, Regenerative Medicine Institute, National University of Ireland Galway, Galway, Ireland

Paul Genever, Department of Biology, University of York, York, UK

Sailaja Ghanta, Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA

Olivier Giet, Laboratory of Cell and Gene Therapy (LTCG), Le Centre Hospitalier Universitaire of Liège and University of Liège, Liège, Belgium

Stuart B. Goodman, Department of Orthopedic Surgery, Stanford University, Stanford, CA, USA

Céline Gregoire, Department of Hematology, Le Centre Hospitalier Universitaire of Liège and Unit of Hematology, University of Liège, Liège, Belgium

Stan Gronthos, Mesenchymal Stem Cell Laboratory, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, South Australia, Australia; Cancer Theme, South Australian Health and Medical Research Institute, Adelaide, SA, Australia

Varun Gudapati, University of California San Francisco, Department of Anesthesiology, San Francisco, CA, USA

P.K. Gupta, Stempeutics Research Pvt Ltd, Whitefield, Bangalore, India

Shanti Gurung, Department of Obstetrics and Gynaecology, Monash University, Victoria, Australia; MIMR-PHI Institute of Medical Research, Clayton, Victoria, Australia

Maria Z. Gutierrez, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia

Joshua Hare, The Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL, USA

Damien G. Harkin, School of Biomedical Sciences, Institute of Health & Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; Queensland Eye Institute, South Brisbane, Australia

Richard P. Harvey, Developmental and Stromal Cell Biology Division, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia; St Vincent's Clinical School and School of Biotechnology, Biomolecular Sciences, University of New South Wales, Kensington, Sydney, Australia

Jessica Hayes, Regenerative Medicine Institute, National University of Ireland Galway, Galway, Ireland

Celena F. Heazlewood, University of Queensland Centre for Clinical Research, Brisbane, Australia

Sarah Elizabeth Hemming, Mesenchymal Stem Cell Laboratory, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, South...

Erscheint lt. Verlag 8.11.2016
Sprache englisch
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie Zellbiologie
Technik
ISBN-10 1-118-90729-9 / 1118907299
ISBN-13 978-1-118-90729-0 / 9781118907290
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