Analytical Ultracentrifugation

Instrumentation, Software, and Applications

Susumu Uchiyama, Fumio Arisaka, Walter F. Stafford, Tom Laue (Herausgeber)

Buch | Hardcover

532 Seiten

2016 | 1st ed. 2016
Springer Verlag, Japan
978-4-431-55983-2 (ISBN)

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This book introduces analytical ultracentrifugation (AUC) as a whole, covering essential theoretical and practical aspects as well as its applications in both biological and non-biological systems. Comprehensive characterizations of macromolecules in a solution are now routinely required not only for understanding the solution system but also for producing a solution with better properties. Analytical ultracentrifugation is one of most powerful and reliable techniques for studying the biophysical behavior of solutes in solution. In the last few years, there have been steady advances made in hardware, software, and applications for AUC.
This book provides chapters that cover everything essential for beginners to the most advanced users and also offer updated knowledge of the field on advances in hardware, software, and applications. Recent development of hardware described in this book covers new detection systems that give added dimensions to AUC. Examples of data analysis with essential theoretical explanations for advanced and recently updated software are also introduced. Besides AUC of biological systems including membrane proteins and biopharmaceuticals, AUC applications for non-biological questions are included. AUC studies under non-ideal conditions such as highly concentrated solutions and solutions with high salt concentration are also included.
The contributors to this book are leading researchers in the fields of solution biophysics and physical chemistry who extensively employ AUC analysis for their research. From this published work, one can gain new and comprehensive knowledge of recent AUC analysis.

Susumu Uchiyama, Ph. D., Associate Professor, Department of Biotechnology, Graduate School of Engineering, Osaka University, 2‐1 Yamadaoka, Suita, Osaka 565‐0871, Japan Fumio Arisaka, Ph. D., Professor, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Midori‐ku, Yokohama 226‐8501, Japan Walter F. Stafford, III, Ph.D., Department of Neurology, Harvard Medical School, Boston, Massachusetts 02115, USA Tom Laue, Ph.D., Professor, Biomolecular Interaction Technologies Center (BITC), Center to Advance Molecular Interaction Science (CAMIS), University of New Hampshire, Rudman Hall, Room 379, 46 CollegeRoad, Durham, NH 03824, USA

Preface.- Part 1: Introduction.- Part 2: AUC Instrumentation and Analysis.- Part 3: Applications of AUC: Material Science.- Part 4: Applications of AUC:Biological Science.- Part 5: Applications of AUC:Biopharmaceuticals.- Part 6: AUC of High-Concentration Systems and Non-ideal Solutions.- Part 7: New Applications of AUC.

Erscheinungsdatum	10.06.2016
Zusatzinfo	117 Illustrations, color; 61 Illustrations, black and white; IX, 532 p. 178 illus., 117 illus. in color.
Verlagsort	Tokyo
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zellbiologie
	Naturwissenschaften ► Chemie ► Analytische Chemie
	Naturwissenschaften ► Chemie ► Organische Chemie
	Technik ► Umwelttechnik / Biotechnologie
Schlagworte	Association–dissociation reaction • Biopharmaceutical formulations • Biophysical behavior of solutes • Inter-molecular interactions • Macromolecules in solution • Non-ideal solutions • Protein–ligand interaction
ISBN-10	4-431-55983-3 / 4431559833
ISBN-13	978-4-431-55983-2 / 9784431559832
Zustand	Neuware