Preventive and Predictive Genetics: Towards Personalised Medicine (eBook)

Godfrey Grech, Iris Grossman (Herausgeber)

eBook Download: PDF

2015 | 2015
XX, 378 Seiten
Springer International Publishing (Verlag)
978-3-319-15344-5 (ISBN)

Infos

Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data.  Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.

Inhalt

IntroductionPreventive and Predictive Genetics: A perspectiveGodfrey Grech, Christian Scerri, Jeanesse Scerri, Tomris CesurogluRoadmap to Drug Development Enabled by PharmacogeneticsJames P Bishop, Sonal B Halburnt, Patrick A Akkari, Scott Sundseth, Iris GrossmanPreventative and Predictive Genetics: Towards Personalised Medicine Aiden Flynn, Craig Ledgerwood & Caroline O’HarePharmacokinetics and Pharmacogenetics: bringing the magic bullet closer to realityJanet Mifsud,  Marc MaliepaardPharmacogenetics of Adverse Drug ReactionsRichard Myles Turner, Munir PirmohamedPharmacogenomics for haemoglobinopathies therapeuticsAikaterini Gravia, Vasiliki Chondrou, Theodora Katsila, George P. PatrinosPharmacogenetics of Neurodegenerative DisordersRamón Cacabelos, Clara Torrellas, Pablo Cacabelos, María J. Villanueva, Sergio Piñeiro, Cristina SolveiraPharmacogenetics of asthmaAnthony G Fenech,  Ian Sayers,  Michael A PortelliPharmacogenetics and antineoplastic therapies Jai N. Patel, Christine M. Walko, Federico InnocentiPharmacogenetics of coumarin anticoagulant therapyRianne M.F. van Schie, Talitha I. Verhoef, Anthonius de Boer, Felix J.M. van der Meer,William K. Redekop, Tom Schalekamp, and Anke-Hilse Maitland-van der ZeeImplementation of Genomic Medicine: tools and challengesGodfrey Grech, Ron van Schaik, Joseph BorgEthical Considerations in the Genomic EraBridget EllulIndex

Produkt-Details

• Erscheint lt. Verlag: 24.6.2015
• Reihe/Serie: Advances in Predictive, Preventive and Personalised Medicine
• Reihe/Serie: Advances in Predictive, Preventive and Personalised Medicine
• Zusatzinfo: XX, 378 p. 18 illus., 8 illus. in color.
• Verlagsort: Cham
• Sprache: englisch
• Themenwelt: Geisteswissenschaften
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
• Themenwelt: Sozialwissenschaften ► Pädagogik
• Themenwelt: Technik
• Schlagworte: antibacterial drug resistance • Biomarkers • drug development • Drug metabolism • Personalised Medicine • Pharmacogenetics / Pharmacogenomics • systems biology
• ISBN-10: 3-319-15344-7 / 3319153447
• ISBN-13: 978-3-319-15344-5 / 9783319153445