Evolutionary Biology (eBook)

Cell-Cell Communication, and Complex Disease

John S. Torday, Virender K. Rehan (Autoren)

eBook Download: EPUB

2012 | 1. Auflage
176 Seiten
John Wiley & Sons (Verlag)
978-1-118-13044-5 (ISBN)

Infos

An integrative view of the evolution of genetics and the natural
world

Even in this advanced age of genomics, the evolutionary process
of unicellular and multicellular organisms is continually in
debate. Evolutionary Biology, Cell-Cell Communication, and
Complex Disease challenges current wisdom by using physiology to
present an integrative view of the nature, origins, and evolution
of fundamental biological systems.

Providing a deeper understanding of the way genes relate to the
traits of living organisms, this book offers useful information
applying evolutionary biology, functional genomics, and cell
communication studies to complex disease. Examining the 4.5
billion-year evolution process from environment adaptations to
cell-cell communication to communication of genetic information for
reproduction, Evolutionary Biology hones in on the "why and how" of
evolution by uniquely focusing on the cell as the smallest unit of
biologic structure and function.

Based on empirically derived data rather than association
studies, Evolutionary Biology covers:

* A model for forming testable hypotheses in complex disease
studies

* The integrating role played by the evolution of metabolism,
especially lipid metabolism

* The evolutionary continuum from development to homeostasis

* Regeneration and aging mediated by signaling molecules

Ambitious and game-changing Evolutionary Biology suggests that
biology began as a mechanism for reducing energy within the cell,
defying the Second Law of Thermodynamics. An ideal text for those
interested in forward thinking scientific study, the insights
presented in Evolutionary Biology help practitioners effectively
comprehend the evolutionary process.

Autor

John Torday, PhD, is Professor of Pediatrics and Ob/Gyn at Harbor-UCLA Medical Center where he is also Director of The Henry L. Guenther Laboratory for Cell/Molecular Research and Director of Laboratory for Evolutionary Preventive Medicine. He is the author of over 130 peer-reviewed articles, Dr. Torday specializes in pre and neo-natal lung development, particularly regarding cell-cell communication within this pathway. V.K. Rehan, MD, is Professor of Pediatrics and Director of the Neonatal Intensive Care Unit at Harbor-UCLA Medical Center. The recipient of numerous teaching honors, Dr. Rehan is involved both in treating patients and continuing research on neo and peri-natal respiratory issues and lung development.

Rezensionen

"...the book offers the biology-savvy reader with
interesting insights into the contribution of cell-cell
interactions to the development and evolution of phenotypes.
Given the technical nature of the subject, this book will have
particular appeal among researchers and students of cellular and
molecular biology and among evolutionary biologists interested in
the pathways linking genes to phenotypes. In keeping with the
complexity of the topic, there is much to digest here, and readers
knowledgeable in these fields will find interesting food for
thought." (Quarterly Reviews in Biology, 1
July 2013)

Produkt-Details

• Erscheint lt. Verlag: 4.9.2012
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Botanik
• Themenwelt: Naturwissenschaften ► Biologie ► Evolution
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zellbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Themenwelt: Technik
• Schlagworte: Biowissenschaften • Cell Biology • Life Sciences • Medical Science • Medizin • Molecular Evolution • Molekulare Evolution • Physiologie • Physiology • Zellbiologie
• ISBN-10: 1-118-13044-8 / 1118130448
• ISBN-13: 978-1-118-13044-5 / 9781118130445