From Molecules to Medicines (eBook)

Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism

Joel L. Sussman, Paola Spadon (Herausgeber)

eBook Download: PDF

2009 | 2009
XV, 251 Seiten
Springer Netherland (Verlag)
978-90-481-2339-1 (ISBN)

Infos

Proceedings of the NATO Advanced Study Institute on Integrating Crystallography in the Fight Against Terrorism
Erice, Italy
29 May-8 June 2008

Inhalt

Preface. List of Contributors. Surface Proteins of Gram-Positive Pathogens: Using Crystallography to Uncover Novel Features in Drug and Vaccine Candidates; E.N. Baker.-
The Rapid Crystallization Strategy for Structure-Based Inhibitor Design; T. Bergfors.- Fragment-Based Drug Discovery in Academia: Experiences from a Tuberculosis Programme; T. Heikkila et al.- Structural Biology Contributions to the Discovery of Drugs to Treat Chronic Myelogenous Leukemia; S.W. Cowan-Jacob et al.- Integrating Crystallography Into Early Metabolism Studies; G. Cruciani et al.- The Foundations of Protein-Ligand Interaction; G. Klebe.- Structure-Based Design of TRNA-Guanine
Transglycosylase Inhibitors; G. Klebe.- Progress on New Hepatitis C Virus Targets: NS2 and NS5A; J. Marcotrigiano.- Protein Structure Modeling; N. Eswar, A. Sali.-
Structural Biology and Molecular Modeling in the Design of Novel DPP-4 Inhibitors; G. Scapin.- Tools to Make 3D Structural Data More Comprehensible: Emovie & Proteopedia; E.Hodis et al.- Structural Studies on Acetylcholinesterase and Paraoxonase Directed Towards Development of Therapeutic Biomolecules for the Treatment of
Degenerative Diseases and Protection against Chemical Threat Agents; J.L.Sussman, Israel Silman.- Protein Function Prediction from Structure in Structural Genomics and Its Contribution to the Study of Health and Disease; J.D. Watson, J.M. Thornton.- Crystal Structures of the ß2-Adrenergic Receptor; W.I. Weis et al.- Can Structures lead to better Drugs? Lessons from Ribosome Research; A.Yonath.-

Produkt-Details

• Erscheint lt. Verlag: 21.4.2009
• Reihe/Serie: NATO Science for Peace and Security Series
• Verlagsort: Dordrecht
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Naturwissenschaften ► Geowissenschaften ► Mineralogie / Paläontologie
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Atom- / Kern- / Molekularphysik
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Festkörperphysik
• Themenwelt: Technik ► Maschinenbau
• Schlagworte: 3D • Bioinformatics • Biology • Chemistry • Computational Chemistry • crystallography • drug discovery • Genome • GPCR • lead • Metabolism • Molecular Modeling • NATO • Peace • protein-crystallization • protein-inhibitor complexes • Science • security • structural biology • structure based d • Sub-Series A
• ISBN-10: 90-481-2339-9 / 9048123399
• ISBN-13: 978-90-481-2339-1 / 9789048123391