Myosins (eBook)

A Superfamily of Molecular Motors

Lynne M. Coluccio (Herausgeber)

eBook Download: PDF

2007 | 2008
XXX, 477 Seiten
Springer Netherland (Verlag)
978-1-4020-6519-4 (ISBN)

Infos

This highly authoritative volume highlights the remarkable superfamily of molecular motors called myosins, which are involved in such diverse cellular functions as muscle contraction, intracellular transport, cell migration and cell division. In a timely compilation of chapters written by leading research groups that have made key discoveries in the field, the current understanding of the molecular mechanisms and biological functions of these intriguing proteins is explored.

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Few would have predicted 20 years ago that myosins constitute a superfamily with at least two-dozen classes and that these molecular motors are involved in a multitude of intracellular activities including cell division, cell movement, intracellular transport and signal transduction. Application of state-of-the-art cellular and molecular biological, structural biological, genetic, biochemical and biophysical techniques has provided and continues to provide critical information regarding the structure-function relationship; and the cellular roles of various myosins in organisms as diverse as protozoa, yeast, plants and higher animals. The association of myosins with diseases including neurological disorders, immu- deficiencies, cardiomyopathies, hearing and vision loss testify to the importance of understanding the biochemical properties and cellular roles of myosins. The 16 chapters in this volume summarize the tremendous progress made in studying members of the myosin superfamily in recent years and offer critical insight into what future research will yield. I would like to express my sincere gratitude to the authors of this volume. It was a pleasure to work with each of you and I thank you for the considerable efforts in making this international endeavor possible. I also thank John Trinick from the University of Leeds, UK, for the elegant montage of images of single molecules of myosins on the cover, which beautifully shows the structures of some of these amazing molecules. The able assistance of Marlies Vlot from Springer and Indumadhi Srinivasan from Integra Software Services for production of the book is greatly appreciated.

Inhalt

The Structural And Functional Diversity Of The Myosin Family Of Actin-Based Molecular Motors.- Myosin Structure.- The Myosin Family: Biochemical And Kinetic Properties.- Myosin I.- Myosin Ii: Sarcomeric Myosins, The Motors Of Contraction In Cardiac And Skeletal Muscles.- Smooth-Muscle Myosin II.- Non-Muscle Myosin II.- Class III Myosins.- Myosin V.- Myosin VI: A Multifunctional Motor Protein.- Myosin VII.- Plant Myosins VIII, XI, And XIII.- Class Ix Myosins.- Myosin X.- Myosin Class XIV And Other Myosins In Protists.- Myosin XVA.

Produkt-Details

• Erscheint lt. Verlag: 15.11.2007
• Reihe/Serie: Proteins and Cell Regulation
• Reihe/Serie: Proteins and Cell Regulation
• Zusatzinfo: XXX, 477 p.
• Verlagsort: Dordrecht
• Sprache: englisch
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zellbiologie
• Themenwelt: Technik
• Schlagworte: biological functions • cell division • Migration • Molecular mechanisms • proteins
• ISBN-10: 1-4020-6519-1 / 1402065191
• ISBN-13: 978-1-4020-6519-4 / 9781402065194