Handbook of Oxidants and Antioxidants in Exercise (eBook)

O. Hanninen, L. Packer, C. Sen (Herausgeber)

eBook Download: PDF

2000 | 1. Auflage
1220 Seiten
Elsevier Science (Verlag)
978-0-08-053829-7 (ISBN)

Infos

Interest in the science of exercise dates back to the time of ancient Greece. Today exercise is viewed not only as a leisurely activity but also as an effective preventive and therapeutic tool in medicine. Further biomedical studies in exercise physiology and biochemistry reports that strenuous physical exercise might cause oxidative lipid damage in various tissues. The generation of reactive oxygen species is elevated to a level that overwhelms the tissue antioxidant defense systems resulting in oxidative stress.

The Handbook of Oxidants and Antioxidants in Exercise examines the different aspects of exercise-induced oxidative stress, its management, and how reactive oxygen may affect the functional capacity of various vital organs and tissues. It includes key related issues such as analytical methods, environmental factors, nutrition, aging, organ function and several pathophysiological processes.

This timely publication will be of relevance to those in biomedical science and was designed to be readily understood by the general scientific audience.

Inhalt

Front Cover 1
Handbook of Oxidants and Antioxidants in Exercise 4
Copyright Page 5
Contents 8
Preface 6
Part I: Introduction to free radicals 12
Chapter 1. Free radical chemistry 14
Part II: Reactive species in tissues 66
Chapter 2. Exercise and oxygen radical production by muscle 68
Chapter 3. Exercise and xanthine oxidase in the vasculature: superoxide and nitric oxide interactions 80
Part III: Oxidative stress: Mechanisms and manifestations 98
Chapter 4. Chemical bases and biological relevance of protein oxidation 100
Chapter 5. Lipid peroxidation in healthy and diseased models: influence of different types of exercise 126
Chapter 6. Metal binding agents: possible role in exercise 140
Chapter 7. The role of xanthine oxidase in exercise 164
Chapter 8. Acute phase immune responses in exercise 188
Chapter 9. Oxidative DNA damage in exercise 206
Part IV: Antioxidant defenses 230
Chapter 10. Physiological antioxidants and exercise training 232
Chapter 11. Superoxide dismutases in exercise and disease 254
Chapter 12. Antioxidants and physical exercise 308
Part V: Nutrition 332
Chapter 13. Dietary sources and bioavailability of essential and nonessential antioxidants 334
Chapter 14. Vitamin E 370
Part VI: Cellular and molecular mechanisms 384
Chapter 15. Biological thiols and redox regulation of cellular signal transduction pathways 386
Chapter 16. Regulation and deregulation of vascular smooth muscle cells by reactive oxygen species and by a-tocopherol 414
Part VII: Analytical methods 442
Chapter 17. Oxidative stress indices: analytical aspects and significance 444
Chapter 18. Noninvasive measures of muscle metabolism 496
Part VIII: Environmental factors 522
Chapter 19. Air pollution and oxidative stress 524
Chapter 20. Risk of oxidative stress at high altitude and possible benefit of antioxidant supplementation 566
Chapter 21. Oxidants in skin pathophysiology 590
Part IX: Organ functions 608
Chapter 22. Muscle fatigue: mechanisms and regulation 610
Chapter 23. Oxidative stress in muscular atrophy 642
Chapter 24. Protection against free radical injury in the heart and cardiac performance 666
Chapter 25. Exercise-induced oxidative stress in the heart 700
Chapter 26. Influence of exercise-induced oxidative stress on the central nervous system 724
Part X: Aging 764
Chapter 27. Oxidants and aging 766
Chapter 28. Caloric restriction, exercise and aging 808
Chapter 29. Oxidative stress and the pathogenesis of sarcopenia 842
Chapter 30. Molecular mechanisms of oxidative stress in aging: free radicals, aging, antioxidants and disease 892
Part XI: Disease processes 936
Chapter 31. Oxidative stress, antioxidants and cancer 938
Chapter 32. Alcohol and oxidative stress 962
Chapter 33. Cigarette smoking as an inducer of oxidative stress in relation to disease pathogenesis 988
Chapter 34. Regulation of inflammation and wound healing 1006
Chapter 35. Oxidative stress induced by the metabolism of medical and nonmedical drugs 1032
Chapter 36. The paradoxical relationship of aerobic exercise and the oxidative theory of atherosclerosis 1064
Chapter 37. Claudication, exercise and antioxidants 1080
Chapter 38. Exercise and oxidative stress in diabetes mellitus 1148
Chapter 39. Exercise induces oxidative stress in healthy subjects and in chronic obstructive pulmonary disease patients 1148
Chapter 40. Hypoxia, oxidative stress and exercise in rheumatoid arthritis 1158
Index of authors 1200
Subject index 1202

Produkt-Details

• Erscheint lt. Verlag: 16.2.2000
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
• Themenwelt: Studium ► Querschnittsbereiche ► Prävention / Gesundheitsförderung
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Ökologie / Naturschutz
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 0-08-053829-0 / 0080538290
• ISBN-13: 978-0-08-053829-7 / 9780080538297