Protein NMR for the Millennium

N. Rama Krishna, Lawrence J. Berliner (Herausgeber)

Buch | Hardcover

341 Seiten

2003
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-47448-4 (ISBN)

Artikel merken

Protein NMR for the Millennium is the third volume in a special thematic series devoted to the latest developments in protein NMR under the Biological Magnetic Resonance umbrella. This book is divided into three major sections dealing with significant recent advances in the study of large proteins in solution and solid state, structure refinement, and screening of bioactive ligands.
Key Features:

TROSY,
Segmental isotope labeling of proteins,
Hydrogen bond scalar couplings,
Structure refinement based on residual dipolar couplings,
Written by the world's foremost experts who have provided broad leadership in advancing the protein NMR field.

Dr. N. Rama Krishna is Professor of Biochemistry and Molecular Genetics and the Director of the NMR Core Facility at the University of Alabama at Birmingham. He has previously served as Guest Editor for Volumes 16 (Modern Techniques in Protein NMR, 1998) and Volume 17 (Structure Computation and Dynamics in Protein NMR, 1999). Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.

Transverse Relaxation Optimized Spectroscopy.- Segmental Isotopic Labeling: Prospects for a New Tool to Study the Structure-function Relationships in Multi-domain Proteins.- Characterization of Inter-Domain Orientations in Solution Using the NMR Relaxation Approach.- Global Fold Determination of Large Proteins using Site-Directed Spin Labeling.- Solid State NMR Studies of Uniformly Isotopically Enriched Proteins.- NMR Spectroscopy of Encapsulated Proteins Dissolved in Low Viscosity Fluids.- Angular Restraints from Residual Dipolar Couplings for Structure Refinement.- Protein Structure Refinement using Residual Dipolar Couplings.- Hydrogen Bond Scalar Couplings — A New Tool In Biomolecular NMR.- NMR Methods for Screening the Binding of Ligands to Proteins — Identification and Characterization of Bioactive Ligands.

Erscheint lt. Verlag	31.1.2003
Reihe/Serie	Biological Magnetic Resonance ; 20
Zusatzinfo	1 Illustrations, color; 126 Illustrations, black and white; XII, 341 p. 127 illus., 1 illus. in color.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Nuklearmedizin
	Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie
	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-306-47448-4 / 0306474484
ISBN-13	978-0-306-47448-4 / 9780306474484
Zustand	Neuware