Target Organ Toxicity
Volume 2
Seiten
2020
CRC Press (Verlag)
978-0-367-25871-9 (ISBN)
CRC Press (Verlag)
978-0-367-25871-9 (ISBN)
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First published in 1986: The purpose of these volumes is to provide a valuable reference for established investigators and postgraduate students in toxicology.
First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
Gerald M. Cohen Ph.D. is Head of the Toxicology Unit, Department of Pharmacology, The School of Pharmacy, University of London.
1. The Kidney as a Target Organ for Toxicity 2. Cardiac Toxicity 3. The Lung as a Target Organ for Toxicity 4. Target Organ Toxicity: The Male Reproductive System 5. Toxic Effects on the Female Reproductive System 6. The Eye 7. The Inner Ear 8. The Endocrine Pancreas as a Target Organ for Toxicity 9. Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction 10. Organ Specificity in Tumor Initiation and Comple Carcinogenesis (Including Species Variation)
| Erscheinungsdatum | 23.07.2019 |
|---|---|
| Reihe/Serie | Routledge Revivals |
| Verlagsort | London |
| Sprache | englisch |
| Maße | 210 x 280 mm |
| Gewicht | 590 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| ISBN-10 | 0-367-25871-4 / 0367258714 |
| ISBN-13 | 978-0-367-25871-9 / 9780367258719 |
| Zustand | Neuware |
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