Target Organ Toxicity

Volume 2

Buch | Hardcover

234 Seiten

2020
CRC Press (Verlag)
978-0-367-25871-9 (ISBN)

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First published in 1986: The purpose of these volumes is to provide a valuable reference for established investigators and postgraduate students in toxicology.

First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Gerald M. Cohen Ph.D. is Head of the Toxicology Unit, Department of Pharmacology, The School of Pharmacy, University of London.

1. The Kidney as a Target Organ for Toxicity 2. Cardiac Toxicity 3. The Lung as a Target Organ for Toxicity 4. Target Organ Toxicity: The Male Reproductive System 5. Toxic Effects on the Female Reproductive System 6. The Eye 7. The Inner Ear 8. The Endocrine Pancreas as a Target Organ for Toxicity 9. Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction 10. Organ Specificity in Tumor Initiation and Comple Carcinogenesis (Including Species Variation)

Erscheinungsdatum	23.07.2019
Reihe/Serie	Routledge Revivals
Verlagsort	London
Sprache	englisch
Maße	210 x 280 mm
Gewicht	590 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-367-25871-4 / 0367258714
ISBN-13	978-0-367-25871-9 / 9780367258719
Zustand	Neuware