Simulation for Designing Clinical Trials

A Pharmacokinetic-Pharmacodynamic Modeling Perspective

Hui Kimko, Stephen B. Duffull (Herausgeber)

Buch | Softcover

424 Seiten

2019
CRC Press (Verlag)
978-0-367-39560-5 (ISBN)

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Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.

Hui C. Kimko, Stephen B. Duffull

Introduction to Simulation for Design of Clinical Trials. Models for Simulation. Computation in Simulation. Analyses of the Simulations. Perspectives on Clinical Trial Simulation. Applications. Index.

Erscheinungsdatum	24.09.2019
Verlagsort	London
Sprache	englisch
Maße	152 x 229 mm
Gewicht	453 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie
	Technik
ISBN-10	0-367-39560-6 / 0367395606
ISBN-13	978-0-367-39560-5 / 9780367395605
Zustand	Neuware