Genetic Mapping and DNA Sequencing

Terry Speed, Michael Waterman (Herausgeber)

Buch | Hardcover

221 Seiten

1996
Springer-Verlag New York Inc.
978-0-387-94803-4 (ISBN)

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Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

An introduction to recombination and linkage analysis.- Monte Carlo methods in genetic analysis.- Interference, heterogeneity and disease gene mapping.- Estimating crossover frequencies and testing for numerical interference with highly polymorphic markers.- What is a genetic map function?.- Haplotyping algorithms.- Statistical aspect of trait mapping using a dense set of markers: a partial review.- A comparative survey of non-adaptive pooling designs.- Parsing of genomic graffiti.- Improving DNA sequencing accuracy and throughput.- Assembly of shotgun sequencing data.

Reihe/Serie	The IMA Volumes in Mathematics and its Applications ; 81
Zusatzinfo	XI, 221 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Mathematik / Informatik ► Mathematik ► Angewandte Mathematik
	Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-387-94803-1 / 0387948031
ISBN-13	978-0-387-94803-4 / 9780387948034
Zustand	Neuware