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Genetic Mapping and DNA Sequencing -

Genetic Mapping and DNA Sequencing

Terry Speed, Michael Waterman (Herausgeber)

Buch | Softcover
221 Seiten
2012 | Softcover reprint of the original 1st ed. 1996
Springer-Verlag New York Inc.
978-1-4612-6890-1 (ISBN)
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Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.
Genetics mapping, physical mapping and DNA sequencing are the three key components of the human and other genome projects. Statistics, mathematics and computing play important roles in all three, as well as in the uses to which the mapping and sequencing data are put. This volume edited by key researchers Mike Waterman and Terry Speed reviews recent progress in the area, with an emphasis on the theory and application of genetic mapping.

An introduction to recombination and linkage analysis.- Monte Carlo methods in genetic analysis.- Interference, heterogeneity and disease gene mapping.- Estimating crossover frequencies and testing for numerical interference with highly polymorphic markers.- What is a genetic map function?.- Haplotyping algorithms.- Statistical aspect of trait mapping using a dense set of markers: a partial review.- A comparative survey of non-adaptive pooling designs.- Parsing of genomic graffiti.- Improving DNA sequencing accuracy and throughput.- Assembly of shotgun sequencing data.

Erscheint lt. Verlag 2.10.2012
Reihe/Serie The IMA Volumes in Mathematics and its Applications ; 81
Zusatzinfo XI, 221 p.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Mathematik / Informatik Mathematik Wahrscheinlichkeit / Kombinatorik
Naturwissenschaften Biologie Zellbiologie
ISBN-10 1-4612-6890-7 / 1461268907
ISBN-13 978-1-4612-6890-1 / 9781461268901
Zustand Neuware
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