Successful Strategies for the Discovery of Antiviral Drugs (eBook)

USA) Desai Manoj C. (Gilead Science Inc., USA) Meanwell Nicholas A. (Bristol-Myers Squibb (Herausgeber)

eBook Download: PDF

2013
544 Seiten
Royal Society of Chemistry (Verlag)
978-1-84973-781-4 (ISBN)

Infos

A focussed and engaging book capturing tactical aspects of problem solving in antiviral drug design.

Inhalt

Section I: Phenotypic Screening to Discover Antiviral Agents; HCV NS5A Inhibitors; RSV fusion Inhibitors; Dengue Virus Inhibitors; Pox Virus Inhibitors; TLR-7 Agonists as Inducers of interferon-α; Section II: Biochemical Screening to Discover Antiviral Agents; HIV Integrase Inhibitors; Inhibitors of Virus Capsid Formation; Ion channels as Antiviral Targets; Section III: Structure- and Physical Property-Based Design of Antiviral Agents; Non-nucleoside HCV NS5B inhibitors; HCV NS3 Protease Inhibitors; HIV Integrase LEDGF inhibitors; Section IV: Delivery of Antiviral Agents; Prodrugs of Nucleoside Analogs for HIV and HCV; Cobicistat and Ritonavir as PK Enhancers for Antiviral drugs; Single Tablet Regimens of Antiviral Agents for HIV and HCV;

Produkt-Details

• Erscheint lt. Verlag: 17.6.2013
• Reihe/Serie: ISSN
• Reihe/Serie: ISSN
• Verlagsort: Cambridge
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Schlagworte: Antiviral • Discovery • Drugs • Strategies • Successful
• ISBN-10: 1-84973-781-9 / 1849737819
• ISBN-13: 978-1-84973-781-4 / 9781849737814