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Formaldehyde and Cognition - Rongqiao He

Formaldehyde and Cognition (eBook)

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2017 | 1st ed. 2017
XIV, 323 Seiten
Springer Netherlands (Verlag)
978-94-024-1177-5 (ISBN)
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This book introduces important, new knowledge regarding formaldehyde, especially endogenous formaldehyde, revealing its many key roles in the human body. It reviews the relationship between endogenous formaldehyde and cognition as well as age-related cognitive impairment, by discussing different aspects such as formaldehyde metabolism, its function in the brain, links with epigenetics and neurophysiology, and epidemiological and clinical investigations. The author also provides suggestions on how to prevent cognitive impairment resulting from excess endogenous formaldehyde. This book appeals to all readers who are interested in cognitive science and toxicology.



Dr. Rongqiao He is a professor at the State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences. He is the vice director of the Chinese Society of Space Research for Biology. He serves as an associate editor for Progress in Biochemistry and Biophysics, and as an editorial board member for Biochimica Biophysica Acta-GS. Dr. He's research focuses on the relationship between the structure and function of neuronal proteins, protein misfolding and neurodegeneration.


This book introduces important, new knowledge regarding formaldehyde, especially endogenous formaldehyde, revealing its many key roles in the human body. It reviews the relationship between endogenous formaldehyde and cognition as well as age-related cognitive impairment, by discussing different aspects such as formaldehyde metabolism, its function in the brain, links with epigenetics and neurophysiology, and epidemiological and clinical investigations. The author also provides suggestions on how to prevent cognitive impairment resulting from excess endogenous formaldehyde. This book appeals to all readers who are interested in cognitive science and toxicology.

Dr. Rongqiao He is a professor at the State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences. He is the vice director of the Chinese Society of Space Research for Biology. He serves as an associate editor for Progress in Biochemistry and Biophysics, and as an editorial board member for Biochimica Biophysica Acta-GS. Dr. He’s research focuses on the relationship between the structure and function of neuronal proteins, protein misfolding and neurodegeneration.

Formaldehyde from environment.- Anabolism and metabolism of formaldehyde in vivo.- Formaldehyde playing a role in (de)methylation for memory.- Dehydration, formaldehyde and age-related cognitive impairment.- The role of formaldehyde in cell proliferation and death.- Gut microbiota, formaldehyde dysmetabolism, and cognitive impairment.- Effects of formaldehyde on protein (Tau) aggregation and cytotoxicity.- Cognitive ability and impairment related to formaldehyde.- Tau phosphorylation and amyloid b deposition in the presence of formaldehyde.- Formaldehyde exposure and neuropsychiatric disorders.- Formaldehyde affecting lifespan and stress resistance in Drosophila.- Potential interventions on formaldehyde induced neuronal toxicity.- Molecular, cellular and animal experiments in formaldehyde study.- Methods in determination of formaldehyde.- Glossary

Erscheint lt. Verlag 20.10.2017
Zusatzinfo XIV, 323 p. 46 illus., 20 illus. in color.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zellbiologie
Naturwissenschaften Biologie Zoologie
Schlagworte Cognitive impairment • epigenetics • Formaldehyde • learning and memory • Neurodegeneration
ISBN-10 94-024-1177-1 / 9402411771
ISBN-13 978-94-024-1177-5 / 9789402411775
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