Clostridial Neurotoxins
The Molecular Pathogenesis of Tetanus and Botulism
Seiten
1995
Springer Berlin (Hersteller)
978-3-540-58452-0 (ISBN)
Springer Berlin (Hersteller)
978-3-540-58452-0 (ISBN)
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This text contains developed information concerning the fundamental aspects of neurotoxins responsible for the neuroparalytic syndromes of tetanus and botulism. The molecular properties in these neurotoxins, responsible for causing disease, are examined as powerful tools in cell biology.
This text describes all biological and biomedical aspects of the action of neurotoxins responsible for the neuroparalytic syndromes of tetanus and botulism. Recently, new fundamental information on the molecular mechanism of action of these neurotoxins has emerged. In particular, clostridial neurotoxins were found to be a new group of zincendopeptidases blocking exocytosis by the very specific cleavage of three protein components of the excoytosis apparatus. This property is described in detail and together with other information, the toxins in the study of cell processes involving their three protein targets can be studied as powerful tools in cell biology and neurosciences.
This text describes all biological and biomedical aspects of the action of neurotoxins responsible for the neuroparalytic syndromes of tetanus and botulism. Recently, new fundamental information on the molecular mechanism of action of these neurotoxins has emerged. In particular, clostridial neurotoxins were found to be a new group of zincendopeptidases blocking exocytosis by the very specific cleavage of three protein components of the excoytosis apparatus. This property is described in detail and together with other information, the toxins in the study of cell processes involving their three protein targets can be studied as powerful tools in cell biology and neurosciences.
| Zusatzinfo | 28 figs. |
|---|---|
| Verlagsort | Berlin |
| Sprache | englisch |
| Gewicht | 565 g |
| Einbandart | gebunden |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
| Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 3-540-58452-8 / 3540584528 |
| ISBN-13 | 978-3-540-58452-0 / 9783540584520 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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