Ras Superfamily Small G Proteins: Biology and Mechanisms 2

Transport

Buch | Softcover

VI, 298 Seiten

2016 | 1. Softcover reprint of the original 1st ed. 2014
Springer International Publishing (Verlag)
978-3-319-37808-4 (ISBN)

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This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.

Prenylation of RabGTPases, their delivery to membranes and Rab recycling.- Rab proteins and the organization of organelle membrane domains.- Effectors of Rab GTPases: Rab binding specificity and their role in coordination of Rab function and localization.- A Rab effector called the exocyst and related vesicle tether complexes.- RabGEFs and GAPs - the enigma variations.- Ran in Nucleocytoplasmic Transport.- Ran in Mitosis.- Arf proteins and their regulators: at the interface between membrane lipids and the protein trafficking machinery.- Small G Proteins: Arf family GTPases in vesicular transport.- ARF-LIKE (ARL) Proteins.- GTPase-Activating Proteins for the Arf-family Small GTPases: not only for the termination.- Rag GTPases.

Erscheinungsdatum	29.08.2016
Zusatzinfo	VI, 298 p. 35 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	biochemistry • Biomedical and Life Sciences • Cell Biology • cellular biology (cytology) • G-Protein effector-interactions • GTPase • GTP binding • Intracellular Transport • nucleo-cytoplasmic transport • Protein Science • Protein Structure • vesicular coats
ISBN-10	3-319-37808-2 / 3319378082
ISBN-13	978-3-319-37808-4 / 9783319378084
Zustand	Neuware