Adipose Tissue and Cancer

Buch | Softcover

190 Seiten

2015 | Softcover reprint of the original 1st ed. 2013
Springer-Verlag New York Inc.
978-1-4899-8919-2 (ISBN)

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Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.

Preface: Obesity, Adipose Tissue and Cancer Progression.- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link.- Increased Adiposity and Colorectal Cancer.- Adiposity and Diabetes in Breast and Prostate Cancer.- Increased Adipocity and Endometrial Cancer Risk.- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer.- Animal Models to Study the Interplay between Cancer and Obesity.- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved.- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment.- The Impact of Obesity Intervention on Cancer: Clinical Perspectives.- Index.

Erscheinungsdatum	17.11.2015
Zusatzinfo	VIII, 190 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	Adipocytes • Adipokines • adiposity • metabolic dysregulation • white adipose tissue
ISBN-10	1-4899-8919-6 / 1489989196
ISBN-13	978-1-4899-8919-2 / 9781489989192
Zustand	Neuware