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Adipose Tissue and Cancer

Mikhail G. Kolonin (Herausgeber)

Buch | Hardcover
190 Seiten
2013 | 2013 ed.
Springer-Verlag New York Inc.
978-1-4614-7659-7 (ISBN)

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Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.

Preface: Obesity, Adipose Tissue and Cancer Progression.- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link.- Increased Adiposity and Colorectal Cancer.- Adiposity and Diabetes in Breast and Prostate Cancer.- Increased Adipocity and Endometrial Cancer Risk.- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer.- Animal Models to Study the Interplay between Cancer and Obesity.- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved.- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment.- The Impact of Obesity Intervention on Cancer: Clinical Perspectives.- Index.

Zusatzinfo VIII, 190 p.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 2. Studienabschnitt (Klinik) Pathologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Adipositas • Krebs (Krankheit)
ISBN-10 1-4614-7659-3 / 1461476593
ISBN-13 978-1-4614-7659-7 / 9781461476597
Zustand Neuware
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