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Photopolymerizable Porous Polyorganophosphazenes

Degradable Matrices for Tissue Engineering

Tamara Bernadette Aigner (Autor)

Buch | Softcover

XIX, 75 Seiten

2015 | 2015
Springer Fachmedien Wiesbaden GmbH (Verlag)
978-3-658-09319-8 (ISBN)

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Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.

Tamara Bernadette Aigner completed her master’s thesis in biological chemistry at Johannes Kepler University in Linz and South Bohemian University in České Budĕjovice.

Polyphosphazenes as Biocompatible and Biodegradable Polymers.- Functionalization and Crosslinking with Thiol-ene Chemistry.- Matrix Formation Using a Photocrosslinking Particulate-Leaching Technique.- Tailored Physical and Biochemical Properties by Blending.

Erscheint lt. Verlag	20.3.2015
Reihe/Serie	BestMasters
Zusatzinfo	XIX, 75 p. 63 illus.
Verlagsort	Wiesbaden
Sprache	englisch
Maße	148 x 210 mm
Gewicht	140 g
Themenwelt	Medizin / Pharmazie ► Pharmazie
	Naturwissenschaften ► Chemie ► Anorganische Chemie
	Technik ► Maschinenbau
Schlagworte	Degradable Polymer • Photo-Crosslinking • Polyphosphazene • Thiol-ene Chemistry • Tissue engineering
ISBN-10	3-658-09319-6 / 3658093196
ISBN-13	978-3-658-09319-8 / 9783658093198
Zustand	Neuware