Biological Basis of Alcohol-Induced Cancer (eBook)
XVI, 436 Seiten
Springer International Publishing (Verlag)
978-3-319-09614-8 (ISBN)
Vasilils Vasiliou, Ph.D., is a Professor of Molecular Toxicology and Director of the Toxicology Graduate Program at the University of Colorado in Denver. He is a reviewer for several journals including Alcohol & Alcoholism, Cancer Letters, International Journal of Cancer. Dr. Vasiliou is also the Editor of the journal, Human Genomics, and also serves on the Editorial Board of several journals, including Journal of Pharmacology and Toxicology. He is a co-editor of Springer publication, Alcohol and Cancer.
Samir Zakhari, Ph.D., is the Senior Vice President of Science at the Distilled Spirits Council of the United States. Prior to Dr. Zakhari's current position, he was the Director of Basic Research at the National Institute on Alcohol Abuse and Alcoholism at the NIH. He is a co-editor of Springer publication, Alcohol and Cancer.
Helmut K. Seitz, MD, is a Distinguished Professor of Medicine, Gastroenterology, and Alcohol Research at the University Heidelberg. He is also the Director of the Salem Medical Center at the University of Heidelberg.
Jan B. Hoek, Ph.D., is a Professor of Pathology, Anatomy, and Cell Biology, as well as Vice-Chair of Research at Thomas Jefferson University.
Vasilils Vasiliou, Ph.D., is a Professor of Molecular Toxicology and Director of the Toxicology Graduate Program at the University of Colorado in Denver. He is a reviewer for several journals including Alcohol & Alcoholism, Cancer Letters, International Journal of Cancer. Dr. Vasiliou is also the Editor of the journal, Human Genomics, and also serves on the Editorial Board of several journals, including Journal of Pharmacology and Toxicology. He is a co-editor of Springer publication, Alcohol and Cancer. Samir Zakhari, Ph.D., is the Senior Vice President of Science at the Distilled Spirits Council of the United States. Prior to Dr. Zakhari's current position, he was the Director of Basic Research at the National Institute on Alcohol Abuse and Alcoholism at the NIH. He is a co-editor of Springer publication, Alcohol and Cancer. Helmut K. Seitz, MD, is a Distinguished Professor of Medicine, Gastroenterology, and Alcohol Research at the University Heidelberg. He is also the Director of the Salem Medical Center at the University of Heidelberg. Jan B. Hoek, Ph.D., is a Professor of Pathology, Anatomy, and Cell Biology, as well as Vice-Chair of Research at Thomas Jefferson University.
Chapter 1: IntroductionChapter 2: Alcohol and breast cancer: Reconciling epidemiological and molecular dataChapter 3: Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinkingChapter 4: Alcohol and Cancer: an Overview With special Emphasis on the Role of Acetaldehyde and Cytochrome P-4502E1Chapter 5: Implications of acetaldehyde-derived DNA adducts for understanding alcohol related carcinogenesisChapter 6: The role of iron in alcohol-mediated hepatocarcinogenesisChapter 7: Alcoholic Cirrhosis and Hepatocellular CarcinomaChapter 8: TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesisChapter 9: Synergistic Toxic Interactions Between CYP2E1, LPS/TNFα and JNK/p38 MAP Kinase and their Implications in Alcohol-induced Liver InjuryChapter 10: Understanding the tumor suppressor PTEN in chronic alcoholism and hepatocellular carcinomaChapter 11: Alcohol consumption, Wnt/-catenin signaling and hepatocarcinogensisChapter 12: Alcohol and HCV: Implications for Liver CancerChapter 13: Application of Mass Spectrometry-based Metabolomics in Identification of Early Noninvasive Biomarkers of Alcohol-Induced Liver Disease Using Mouse ModelChapter 14: Alcohol Metabolism by Oral Streptococci and Interaction with Human Papillomavirus Leads to Malignant Transformation of Oral KeratinocytesChapter 15: Genetic polymorphisms of alcohol dehydrogense-1B and aldehyde dehydrogenase-2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkersChapter 16: Acetaldehyde and Retinaldehyde-Metabolizing Enzymes in Colon and Pancreatic cancersChapter 17: Alcohol, Carcinoembryonic Antigen Processing and Colorectal Liver MetastasesChapter 18: Alcohol Consumption and Antitumor Immunity: Dynamic Changes from Activation to Accelerated Deterioration of the Immune SystemChapter 19: A Perspective on Chemoprevention by Resveratrol in Head and Neck Squamous Cell CarcinomaChapter 20: The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesisChapter 21: The effect of alcohol on sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC)Chapter 22: Transgenic Mouse Models for Alcohol Metabolism, Toxicity and CancerChapter 23: Fetal alcohol exposure increases susceptibility to carcinogenesis and promotes tumor progression in prostate glandChapter 24: Fetal Alcohol Exposure and Mammary Tumorigenesis in Offspring: Role of the Estrogen and Insulin-like Growth Factor Systems
| Erscheint lt. Verlag | 26.11.2014 |
|---|---|
| Reihe/Serie | Advances in Experimental Medicine and Biology | Advances in Experimental Medicine and Biology |
| Zusatzinfo | XVI, 436 p. 97 illus., 57 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie |
| Naturwissenschaften ► Biologie | |
| Technik | |
| Schlagworte | acetaldehyde • Cirrhosis • Hepatocarcinogenesis • Liver Cancer |
| ISBN-10 | 3-319-09614-1 / 3319096141 |
| ISBN-13 | 978-3-319-09614-8 / 9783319096148 |
| Haben Sie eine Frage zum Produkt? |
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