Glycobiology of the Nervous System (eBook)
XVII, 584 Seiten
Springer New York (Verlag)
978-1-4939-1154-7 (ISBN)
A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
1 Introduction to the Complexity of Cell Surface and Tissue Matrix GlycoconjugatesVeer P. Bhavanandan, D. Channe Gowda2 Introduction to Cells Comprising the Nervous SystemDouglas G. Peters, James R. Connor3 Synthesis, Processing, and Function of N-glycans in N-glycoproteinsErhard Bieberich4 Synthesis of O-linked Glycoconjugates in the Nervous SystemJin-Ichi Inokuchi, Shinji Go, Yoshio Hirabayashi5 Chemistry and Function of Glycosaminoglycans in the Nervous SystemNancy B. Schwartz, Miriam S. Domowicz6 Use of Glycan-targeted Antibodies/Lectins to Study the Expression/Function of Glycosyltransferases in the Nervous SystemYasuhiko Kizuka, Kenji Kanekiyo, Shinobu Kitazume, Naoyuki Taniguchi7 From Mass Spectrometry-based Glycosylation Analysis to Glycomics and GlycoproteomicKay-Hooi Khoo8 Structural Analysis of Oligosaccharides and Glycoconjugates using NMRYoshiki Yamaguchi, Takumi Yamaguchi, Koichi Kato9 Glycolipid and Glycoprotein Expression During Neural DevelopmentRobert K. Yu, Yutaka Itokazu10 Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous SystemMassimo Aureli, Maura Samarani, Valentina Murdica, Laura Mauri, Nicoletta Loberto, Rosaria Bassi, Alessandro Prinetti, Sandro Sonnino11 Role of Myelin-Associated Glycoprotein (Siglec-4a) in the Nervous SystemPablo H.H. Lopez12 Role of Galactosylceramide and Sulfatide in Oligodendrocytes and CNS Myelin: Formation of a GlycosynapseJoan M. Boggs13 Glycosignaling – A General ReviewGlyn Dawson14 Glycosphingolipids in the Regulation of the Nervous SystemKoichi Furukawa, Yusuke Ohmi, Yuki Ohkawa, Orie Tajima, Keiko Furukawa15 Glycobiology of Ion Transport in the Nervous SystemMartha C. Nowycky, Gusheng Wu, Robert W. Ledeen16 O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in NeurodegenerationOlof Lagerlöf, Gerald W. Hart17 N-glycosylation in Regulation of the Nervous SystemHilary Scott, Vladislav M. Panin18 Roles of Carbohydrates in the Interaction of Pathogens with Neural CellsCara-Lynne Schengrund19 Glycoconjugate Changes in Aging and Age-related DiseasesSusumu Ando20 Gangliosides and Glycolipids in Neurodegenerative DisordersJ. S. Schneider21 Glycosidases: Inborn Errors of Glycosphingolipid CatabolismHisashi Ashida, Yu-Teh Li22 Ganglioside Storage Diseases: On the Road to ManagementThomas N. Seyfried, Hannah E. Rockwell, Karie A. Heinecke, Douglas R. Martin, Miguel Sena-Esteves23 Dynamic Aspects of Neural Tumor GangliosidesStephan Ladisch, Yihui Liu24 Galectins and NeuroinflammationHung-Lin Chen, Fang Liao, Teng-Nan Lin, Fu-Tong Liu25 Glycoconjugates and Neuroimmunological DiseasesHugh J. Willison
| Erscheint lt. Verlag | 23.8.2014 |
|---|---|
| Reihe/Serie | Advances in Neurobiology | Advances in Neurobiology |
| Zusatzinfo | XVII, 584 p. 123 illus., 59 illus. in color. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Technik | |
| Schlagworte | glycobiology • glycoconjugates • Glycolipids • Lectins • N- and O-linked glycoproteins • nerve cell differentiation |
| ISBN-10 | 1-4939-1154-6 / 1493911546 |
| ISBN-13 | 978-1-4939-1154-7 / 9781493911547 |
| Haben Sie eine Frage zum Produkt? |
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