Focal Controlled Drug Delivery (eBook)
XVII, 700 Seiten
Springer US (Verlag)
978-1-4614-9434-8 (ISBN)
ABRAHAM J. DOMB is Professor for Medicinal Chemistry and Biopolymers at the Faculty of Medicine of the Hebrew University in Jerusalem, Israel. He earned bachelor's degrees in chemistry, pharmacy and law studies and a Ph.D. in chemistry from Hebrew University. He did his postdoctoral training at MIT and Harvard University and was R&D manager at Nova Pharm in Baltimore between 1988 and 1992. His primary research interests are in biopolymers, controlled drug delivery, cancer therapy, nanoparticulate systems, and forensic sciences.
WAHID KHAN obtained his master's degree and Ph.D. in pharmaceutics at the National Institute of Pharmaceutical & Educational Research (NIPER) in Mohali, India. He worked with Prof. Abraham J. Domb in The Hebrew University of Jerusalem, Israel, for his post-doctoral research. Currently, he is working as Assistant Professor in the Department of Pharmaceutics at NIPER in Hyderabad, India. His experience includes areas ranging from drug delivery and drug targeting to nanomedicine and biodesign of implantable medical devices.
The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.
ABRAHAM J. DOMB is Professor for Medicinal Chemistry and Biopolymers at the Faculty of Medicine of the Hebrew University in Jerusalem, Israel. He earned bachelor’s degrees in chemistry, pharmacy and law studies and a Ph.D. in chemistry from Hebrew University. He did his postdoctoral training at MIT and Harvard University and was R&D manager at Nova Pharm in Baltimore between 1988 and 1992. His primary research interests are in biopolymers, controlled drug delivery, cancer therapy, nanoparticulate systems, and forensic sciences. WAHID KHAN obtained his master’s degree and Ph.D. in pharmaceutics at the National Institute of Pharmaceutical & Educational Research (NIPER) in Mohali, India. He worked with Prof. Abraham J. Domb in The Hebrew University of Jerusalem, Israel, for his post-doctoral research. Currently, he is working as Assistant Professor in the Department of Pharmaceutics at NIPER in Hyderabad, India. His experience includes areas ranging from drug delivery and drug targeting to nanomedicine and biodesign of implantable medical devices.
1. Biodegradable Polymers for Focal Delivery SystemsWahid Khan, Venu Gopala Swami Challa, Robert Langer, and Abraham J. Domb 2. Implantable Medical DevicesWahid Khan, Eameema Muntimadugu, Michael Jaffe, and Abraham J. Domb 3. Systemic Targeting Systems-EPR Effect, Ligand Targeting SystemsPrasad V. Pawar, Abraham J. Domb, and Neeraj Kumar 4. Liposomal formulations for Focal and Targeted Drug Delivery in Cancer and Other DiseasesSean Essex and Vladimir Torchilin 5. Polymer Drug Conjugate in Focal Drug DeliveryRajan Swami, Dinesh Kumar, Wahid Khan, Ramakrishna Sistla, Nalini Shastri 6. Pharmacokinetic and Pharmacodynamic Aspects of Focal and Targeted Delivery of DrugsDavid Stepensky 7. Treatment of Brain Tumors Betty M. Tyler, Gustavo Pradilla, Uri Hadelsberg, Hansen Bow, and Henry Brem 8. Intranasal Delivery of Neuropeptide-Loaded Nanoparticles and Their Application to Nervous System TherapeuticsMichael J. Kubek, Abraham J. Domb, Daniel J. Kubeka, Michael C. Veronesi 9. Focal Drug Delivery in Inner Ear TherapyJing Zou 10. Nanotechnology Based Ophthalmic Drug Delivery SystemFahima Dilnawaz and Sanjeeb Kumar Sahoo 11. Site Specific Ocular Nucleic Acid Delivery Ravi S. Shukla and Kun Cheng 12. Topical Iontophoresis for Targeted Local Drug Delivery to the Eye and SkinTaís Gratieri and Yogeshvar N. Kalia 13. Local Drug Delivery to the Oral CavitySheeba Qureshi, Wahid Khan, Michael Perez-Davidi, Ervin I Weiss, Nurit Beyth, and Abraham J. Domb 14. Focal Drug Delivery for Management of Oral Infections Nurit Beyth, Orith Haramaty and David Polak 15. Segmental-Dependent Drug Absorption and Delivery: The StomachOmri Wolk and Arik Dahan 16. Segmental-Dependent Drug Absorption and Delivery: The Intestinal TractOmri Wolk and Arik Dahan 17. Nanotechnology Applications in Local Arterial Drug DeliveryDipti Deshpande, Azizah Jamal-Allial, Kinjal Sankhe, and Mansoor Amiji 18. Drug Eluting Stents Wahid Khan, Rajesh Thipparaboina, Shady Farah, Judah Z. Weinberger, and Abraham J. Domb 19. Drug-Eluting Vascular GraftsJingjia Han and Peter I. Lelkes 20. Delivery Systems for Lymphatic TargetingIndu Singh, Rajan Swami, Wahid Khan, and Ramakrishna Sistla 21. Spatio-temporal Focal Delivery of Dual Regenerating Factors for Osteochondral Defect RepairEmil Ruvinov and Smadar Cohen 22. Spatio-temporal Focal Delivery of Dual Regenerating Factors for Osteochondral Defect RepairEmil Ruvinov and Smadar Cohen 23. Polymer Based Drug Delivery Systems for Solid Tumor TreatmentAriella Shikanov and Abraham J. Domb 24. Topical Nanointerventions for Therapeutic and Cosmeceutical ApplicationsVandana B. Patravale and Preshita P. Desai 25. Focal Drug Delivery to the NailSudaxshina Murdan 26. Drug Delivery to Wounds, Burns and Diabetes Related UlcersSonam Jain, Abraham J. Domb, and Neeraj Kumar 27. Vaginal Drug DeliveryEmily A. Krogstad, Michael J. Rathbone, and Kim A. Woodrow 28. Prolonged Duration Local AnesthesiaJ. Brian McAlvin and Daniel S. Kohane
| Erscheint lt. Verlag | 17.2.2014 |
|---|---|
| Reihe/Serie | Advances in Delivery Science and Technology | Advances in Delivery Science and Technology |
| Zusatzinfo | XVII, 700 p. 100 illus., 75 illus. in color. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Pflege |
| Medizin / Pharmazie ► Pharmazie ► PTA / PKA | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie | |
| Naturwissenschaften ► Chemie | |
| Technik | |
| Schlagworte | biopolymers • focal controlled drug delivery • iontophoresis • Liposomes • nanoparticles • targeted delivery |
| ISBN-10 | 1-4614-9434-6 / 1461494346 |
| ISBN-13 | 978-1-4614-9434-8 / 9781461494348 |
| Haben Sie eine Frage zum Produkt? |
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