Cellular and Molecular Toxicology and In Vitro Toxicology

Daniel Acosta (Autor)

Buch | Softcover

176 Seiten

1990
Crc Press Inc (Verlag)
978-0-8493-4421-3 (ISBN)

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This work concentrates on cellular and molecular toxicity of selected well-known drugs or chemicals on the cardiovascular system. The primary objective is to provide a better understanding of the mechanisms by which xenobiotics are toxic to mammalian tissues and cells. The use of in vitro cellular and tissue systems provides attractive experimental models to assess toxic manifestations of xenobiotics. This work addresses the most recent findings on the cellular and molecular mechanisms of toxicity of several important cardiotoxic agents: doxorubicin, ethanol, cocaine, and the catecholamines. It presents an overview of vascular toxins and their biochemical effects. Included is a summary of in vitro cardiovascular techniques for assessing toxicity of xenobiotics. This publication is important for those in toxicology, tissue culture, pharmacology, in vitro toxicology, developmental biology and related areas.

The Vascular Toxicity of Xenobiotics (P.J. Boor). The Molecular and Cellular Toxicology of Ethanol on the Heart (P.I. Polimeni and P. Posner). Mechanisms of Anthracycline Cardiotoxicity: Are Metabolites Involved (R.D. Olson and P.S. Mushlin). Cardiotoxicity of Catecholamines (G.L. Todd). The Toxic Effects of Cocaine on the Heart (A.A. Welder). Cellular and Molecular Basis of Xenobiotic-Induced Cardiovascular Toxicity: Application of Cell Culture Systems (K. Ramos). Index.

Erscheint lt. Verlag	22.8.1990
Verlagsort	Bosa Roca
Sprache	englisch
Maße	152 x 229 mm
Gewicht	408 g
Einbandart	Paperback
Themenwelt	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-8493-4421-2 / 0849344212
ISBN-13	978-0-8493-4421-3 / 9780849344213
Zustand	Neuware