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Antimicrobial Compounds

Current Strategies and New Alternatives
Buch | Hardcover
XVI, 316 Seiten
2013 | 2014
Springer Berlin (Verlag)
978-3-642-40443-6 (ISBN)

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Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years.

This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.

Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining.- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials.- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications.- New antimicrobial agents of plant origin.- Advances in beta-lactam antibiotics.- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria.- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds.- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB).- New cell wall-affecting antifungal antibiotics.- Perspectives in the research on Antimicrobial peptides.- Glycopeptides and bacterial cell walls.

Erscheint lt. Verlag 30.10.2013
Zusatzinfo XVI, 316 p. 47 illus., 18 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 635 g
Themenwelt Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Antibiotics • Anti-fungal compounds • Anti-viral compounds • drug design • Drug resistant bacteria
ISBN-10 3-642-40443-X / 364240443X
ISBN-13 978-3-642-40443-6 / 9783642404436
Zustand Neuware
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