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Antimicrobial Compounds -

Antimicrobial Compounds

Current Strategies and New Alternatives
Buch | Softcover
XVI, 316 Seiten
2016 | 1. Softcover reprint of the original 1st ed. 2014
Springer Berlin (Verlag)
978-3-662-51216-6 (ISBN)
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This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. It combines basic research with clinical applications.

Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years.

This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.

Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining.- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials.- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications.- New antimicrobial agents of plant origin.- Advances in beta-lactam antibiotics.- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria.- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds.- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB).- New cell wall-affecting antifungal antibiotics.- Perspectives in the research on Antimicrobial peptides.- Glycopeptides and bacterial cell walls.

Erscheinungsdatum
Zusatzinfo XVI, 316 p. 47 illus., 18 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Antibiotics • Anti-fungal compounds • Anti-viral compounds • Biomedical and Life Sciences • drug design • Drug resistant bacteria • Genetics (non-medical) • Industrial chemistry and chemical engineering • Medical Microbiology • Medical microbiology and virology • Microbial Genetics and Genomics • Microbiology • Microbiology (non-medical) • Pharmaceutical Sciences/Technology
ISBN-10 3-662-51216-5 / 3662512165
ISBN-13 978-3-662-51216-6 / 9783662512166
Zustand Neuware
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