Copper–Oxygen Chemistry
John Wiley & Sons Inc (Hersteller)
978-1-118-09436-5 (ISBN)
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Kenneth D. Karlin is Ira Remsen Professor of Chemistry at Johns Hopkins University. His bioinorganic research focuses on coordination chemistry relevant to biological and environmental processes, involving copper or heme (porphyrin-iron) complexes. Dr. Karlin's main approach involves synthetic modeling, i.e., biomimetic chemistry. He is the winner of the prestigious F. Albert Cotton Award in Synthetic Inorganic Chemistry and the Sierra Nevada Distinguished Chemist Award, both awarded in 2009. Shinobu Itoh focuses his current research on chemical modeling and application of novel active sites in biological systems. He was formerly an assistant professor at Osaka University, where he worked on the chemistry of coenzyme PQQ and cofactor TTQ as well as model compounds of galactose oxidase. In 1994, he was promoted to associate professor at Osaka University, where he collaborated with Professor Shunichi Fukuzumi in copper-dioxygen chemistry research. In 1999, he moved to Osaka City University as a full professor and started biological studies of dinuclear copper proteins, such as hemocyanin and tyrosinase. He returned to Osaka University in 2008 and further expanded his research interests to the design of artificial non-heme metalloenzymes using genetic engineering.
Preface to Series vii Introduction ix Contributors xi 1 Insights into the Proposed Copper-Oxygen Intermediates that Regulate the Mechanism of Reactions Catalyzed by Dopamine b-Monooxygenase, Peptidylglycine a-Hydroxylating Monooxygenase, and Tyramine b-Monooxygenase 1 Robert L. Osborne and Judith P. Klinman 2 Copper Dioxygenases 23 Jozsef Kaizer, Jozsef Sandor Pap, and Gabor Speier 3 Amine Oxidase and Galactose Oxidase 53 Dalia Rokhsana, Eric M. Shepard, Doreen E. Brown, and David M. Dooley 4 Energy Conversion and Conservation by Cytochrome Oxidases 107 Angela Paulus and Simon de Vries 5 Multicopper Proteins 131 Takeshi Sakurai and Kunishige Kataoka 6 Structure and Reactivity of Copper-Oxygen Species Revealed by Competitive Oxygen-18 Isotope Effects 169 Justine P. Roth 7 Theoretical Aspects of Dioxygen Activation in Dicopper Enzymes 197 Kazunari Yoshizawa 8 Chemical Reactivity of Copper Active-Oxygen Complexes 225 Shinobu Itoh 9 Cytochrome c Oxidase and Models 283 Zakaria Halime and Kenneth D. Karlin 10 Supramolecular Copper Dioxygen Chemistry 321 Jean-Noel Rebilly and Olivia Reinaud 11 Organic Synthetic Methods Using Copper Oxygen Chemistry 361 Marisa C. Kozlowski Index 445
| Erscheint lt. Verlag | 12.8.2011 |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 150 x 250 mm |
| Gewicht | 666 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Chemie | |
| ISBN-10 | 1-118-09436-0 / 1118094360 |
| ISBN-13 | 978-1-118-09436-5 / 9781118094365 |
| Zustand | Neuware |
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