Stem Cells and Cancer Stem Cells, Volume 7 (eBook)

Therapeutic Applications in Disease and Injury

M.A. Hayat (Herausgeber)

eBook Download: PDF

2012 | 2012
XXII, 278 Seiten
Springer Netherland (Verlag)
978-94-007-4285-7 (ISBN)

Infos

The seventh in Springer's landmark series of edited volumes on one of the highest-profile subjects in contemporary medicine and scientific endeavour, this volume sets out to cover a staggering range of research into the medical applications of stem cell research. While stem cells are the very stuff of life for multicellular organisms, including us humans, the cancer stem cell is a morbid entity with a robust resistance to therapies including conventional chemotherapy. This authoritative publication explains the regenerative potential of stem cells and their mesenchymal progeny, reviewing clinical applications of the latter in the treatment of cancer, diabetes and neurodegenerative pathologies. It covers the entire range of stem cells with known potential for therapeutic use, from human embryonic to germ cell-derived pluripotent stem cells and hematopoietic stem cells. The chapters also deal with the role of TGF-beta in propagating human embryonic stem cells, and in facilitating their differentiation. Featuring discussions of molecular signaling pathways that modulate mesenchymal stem cell self-renewal and much more, this book is certain to have broad appeal among academicians and physicians alike.

Inhalt

I.    Regenerative medicine1: Mesenchymal stem cell expansion for therapeutic application 6: Mobilization of pluripotent stem cells in patients with myocardial ischemia: from the bench to bedside2: Role of induced pluripotent stem cells in regenerative medicine3: Sulforaphane as new therapeutic agent for targeting of cancer stem cells with focus to prostate and pancreatic cancer4: Technology platforms for heart regenerative therapy using pluripotent stem cells5: Myocardial regeneration of adipose tissue-derived stem cells: differentiation, paracrine, fusion mechanisms 7: Mammary regeneration using embryonic stem cell engraftment8: Recovery of the bone marrow in lethally irradiated host: role of hyper-activated stem cell factor receptor9: Potential of bone marrow-derived stem cells in treatment of genetic diseases of the liver10: Propagation of human bone marrow stem cells for craniofacial applications11: Maintenance of pluripotency in mouse stem cells: use of hyaluronan in the long-term culture12: Initiation of soft tissue sarcomas: muscle stem/progenitor cells as targets13: Mesenchymal stem cells: complex players in lung repair & injuryII. Tissue engineering

Produkt-Details

• Erscheint lt. Verlag: 12.6.2012
• Reihe/Serie: Stem Cells and Cancer Stem Cells
• Reihe/Serie: Stem Cells and Cancer Stem Cells
• Zusatzinfo: XXII, 278 p. 50 illus., 38 illus. in color.
• Verlagsort: Dordrecht
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Innere Medizin
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Technik
• Schlagworte: Cancer Therapy • Regenerative medicine • Tissue engineering • Transplantation • Treatment of tissue/organ injury
• ISBN-10: 94-007-4285-1 / 9400742851
• ISBN-13: 978-94-007-4285-7 / 9789400742857