Early Life Origins of Health and Disease (eBook)
XVIII, 228 Seiten
Springer US (Verlag)
978-0-387-32632-0 (ISBN)
Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone. There is good evidence that stress and more subtle dietary deficiencies, as well as placental malfunction, may increase the risk that the offspring will develop these problems in later life. Finally, new and emerging evidence for other areas of human health and disease such a motor control and mental health is critically reviewed for the first time. The book is a 'must' for all scientists interested in researching these areas, as there is a critical evaluation of the methodology used and suggestions for the 'optimal' way in which to investigate these phenomena.
Professor Owens is an internationally recognized researcher in developmental physiology and endocrinology and in the early life programming of adult health and disease, diabetes and obesity in particular. She has published over 140 research papers, reviews and book chapters. She has been invited to present numerous plenary lectures or symposia at international or national conferences, and to convene and chair international symposia and plenary sessions at the First, Second and Third World Congresses for the Developmental Origins of Adult Health and Disease (previously Fetal Origins of Adult Disease). She was awarded the McCance Medal for outstanding contributions to perinatal research.
Early Life Origins of Health and Disease is a new book which presents and discusses the many factors that may have impact on normal development. In a concise and readable manner, the authors consider both the proven and suggestive evidence that the high prevalence of hypertension, diabetes, obesity and, in some populations, kidney disease, may not be all due to genetics or adult environment alone. There is good evidence that stress and more subtle dietary deficiencies, as well as placental malfunction, may increase the risk that the offspring will develop these problems in later life. Finally, new and emerging evidence for other areas of human health and disease such a motor control and mental health is critically reviewed for the first time. The book is a 'must' for all scientists interested in researching these areas, as there is a critical evaluation of the methodology used and suggestions for the 'optimal' way in which to investigate these phenomena.
Professor Owens is an internationally recognized researcher in developmental physiology and endocrinology and in the early life programming of adult health and disease, diabetes and obesity in particular. She has published over 140 research papers, reviews and book chapters. She has been invited to present numerous plenary lectures or symposia at international or national conferences, and to convene and chair international symposia and plenary sessions at the First, Second and Third World Congresses for the Developmental Origins of Adult Health and Disease (previously Fetal Origins of Adult Disease). She was awarded the McCance Medal for outstanding contributions to perinatal research.
The Developmental Origins of Health and Disease.- The Developmental Origins of Health and Disease.- Should we intervene to improve fetal growth?.- Developmental Origins of Cardiovascular Disease, Type 2 Diabetes and Obesity in Humans.- Growth and development of human twins.- Studies of Twins.- Practice-induced plasticity in the human motor cortex.- Prenatal Programming of Human Motor Function.- Adaptive Responses of Early Embryos to Their Microenvironment and Consequences for Post-Implantation Development.- Adaptive Responses of Early Embryos to Their Microenvironment and Consequences for Post-Implantation Development.- Modification of Epigenetic State through Dietary Manipulation in the Developing Mammalian Embryo.- Modification of Epigenetic State through Dietary Manipulation in the Developing Mammalian Embryo.- Overview of epigenetic mechanisms.- Critical Experiments to Determine if Early Nutritional Influences on Epigenetic Mechanisms Cause Metabolic Imprinting in Humans.- Nutritional programming and the development of hypertension.- Manipulation of the Maternal Diet in Rat Pregnancy.- Hypertension in pregnant women.- Programming Hypertension—Animal Models.- Developmental Programming of Cardiovascular Dysfunction.- Developmental Programming of Cardiovascular Dysfunction.- Kidney Development and Fetal Programming.- Kidney Development and Fetal Programming.- Programming of Obesity—Experimental Evidence.- Programming of Obesity—Experimental Evidence.- Placental delivery of amino acids. Utilization and production vs. transport.- Perinatal Programming of Adult Metabolic Homeostasis.- Programming Effects of Excess Glucocorticoid Exposure in Late Gestation.- Programming Effects of Excess Glucocorticoid Exposure in Late Gestation.- Emerging Frontiers.- Programming Effects of Moderate and Binge Alcohol Consumption.- Vitamin D in Pregnancy and Offspring Health.- The Fetal Origins of Adult Mental Illness.- Hypoxia, Fetal Growth and Developmental Origins of Health and Disease.
| Erscheint lt. Verlag | 26.2.2007 |
|---|---|
| Reihe/Serie | Advances in Experimental Medicine and Biology | Advances in Experimental Medicine and Biology |
| Zusatzinfo | XVIII, 228 p. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Allgemeinmedizin |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe | |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Technik | |
| Schlagworte | Amino Acids • Development • Diabetes • Embryo • Genetics • growth • Health • Implantation • Imprinting • Nutrition • Obesity • placenta • Pregnancy • Stress |
| ISBN-10 | 0-387-32632-4 / 0387326324 |
| ISBN-13 | 978-0-387-32632-0 / 9780387326320 |
| Haben Sie eine Frage zum Produkt? |
PDF (Wasserzeichen)Größe: 17,0 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich
