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Neuroimaging Part B -

Neuroimaging Part B (eBook)

Michael F. Glabus (Herausgeber)

eBook Download: PDF
2005 | 1. Auflage
488 Seiten
Elsevier Science (Verlag)
978-0-08-047860-9 (ISBN)
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173,35 inkl. MwSt
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Comprised of two separate volumes, Neuroimaging provides a state-of-the-art review of a broad range of neuroimaging techniques applied to both clinical and research settings. The breadth of the methods covered is matched by the depth of description of the theoretical background. Part B covers the application of neuroimaging in both research and clinical settings for the study of anxiety disorders, dementia, depression, schizophrenia, functional somatic syndromes, stroke, and multiple sclerosis using a range of neuroimaging modalities including CT, PET, SPECT, DTI, structural MRI and fMRI. One chapter is devoted to the study of brain development using structural MRI, and one chapter to the study of pediatric neurobehavioral disorders using fMRI. One of the most exciting recent applications of neuroimaging to the area of genetics is covered, and with the theory and application of neuroreceptor imaging in psychiatry, forms the final two chapters.

The two parts of Neuroimaging complement each other providing in-depth information on a broad range of routine and cutting edge techniques that is not available in any other text. This book is superbly written and beautifully illustrated by contributors working at the top of their chosen specialty.

* Presents recent applications of neuroimaging to the area of genetics
* Discusses the study of brain development using structural MRI
* Includes chapters on the theory and application of neuroreceptor imaging in psychiatry
Comprised of two separate volumes, Neuroimaging provides a state-of-the-art review of a broad range of neuroimaging techniques applied to both clinical and research settings. The breadth of the methods covered is matched by the depth of description of the theoretical background. Part B covers the application of neuroimaging in both research and clinical settings for the study of anxiety disorders, dementia, depression, schizophrenia, functional somatic syndromes, stroke, and multiple sclerosis using a range of neuroimaging modalities including CT, PET, SPECT, DTI, structural MRI and fMRI. One chapter is devoted to the study of brain development using structural MRI, and one chapter to the study of pediatric neurobehavioral disorders using fMRI. One of the most exciting recent applications of neuroimaging to the area of genetics is covered, and with the theory and application of neuroreceptor imaging in psychiatry, forms the final two chapters. The two parts of Neuroimaging complement each other providing in-depth information on a broad range of routine and cutting edge techniques that is not available in any other text. This book is superbly written and beautifully illustrated by contributors working at the top of their chosen specialty. - Presents recent applications of neuroimaging to the area of genetics- Discusses the study of brain development using structural MRI- Includes chapters on the theory and application of neuroreceptor imaging in psychiatry

Cover 1
Title Page 2
Series Editors 3
Copyright Page 5
Contents 6
Contributors 10
Chapter 1: Distinguishing Neural Substrates of Heterogeneity Among Anxiety Disorders 13
I. Obsessive-Compulsive Disorder 16
II. Posttraumatic Stress Disorder 21
III. Panic Disorder 25
IV. Specific Phobia (Simple Phobia) 29
V. Social Phobia (Social Anxiety Disorder) 31
VI. Generalized Anxiety Disorder 35
VII. Discussion 39
Acknowledgments 41
References 41
Chapter 2: Neuroimaging in Dementia 55
I. Introduction 56
II. Dementia 56
III. Imaging Modes 59
IV. Diagnostic Imaging 60
V. Functional Imaging 68
VI. Pharmacological Imaging 72
VII. Conclusion 75
References 76
Chapter 3: Prefrontal and Anterior Cingulate Contributions to Volition in Depression 85
I. Defining Volition and Outlining its Relationship to Depression 86
II. DLPFC and Volition 88
III. DLPFC and Depression 91
IV. ACC and Volition 93
V. ACC and Depression 95
VI. DLPFC and ACC in Volition: Synthesis and Future Directions for Depression Research 97
Acknowledgments 99
References 99
Chapter 4: Functional Imaging Research in Schizophrenia 107
I. Psychomotor Disturbances 109
II. Early Visual Processing Deficits 110
III. Auditory System 112
IV. Selective Attention 114
V. Working Memory Dysfunction 116
VI. Antipsychotic Drug Effects 118
VII. Neuroimaging Genomics 119
References 124
Chapter 5: Neuroimaging in Functional Somatic Syndromes 131
I. Introduction 131
II. The Disorders 133
III. Discussion and Conclusions 163
References 167
Chapter 6: Neuroimaging in Multiple Sclerosis 177
I. Introduction 178
II. Clinical Manifestations 185
III. The Pathology of MS as it Relates to Neuroimaging 186
IV. MRI in Multiple Sclerosis 187
V. SPECT and PET Scanning 197
VI. The Neuroimaging of Neuropsychological Dysfunction in Multiple Sclerosis 201
References 208
Chapter 7: Stroke 215
I. Introduction 216
II. Brain Scan in Acute Stroke 218
III. Clinical Utility of MRI Brain Scan in Acute Stroke 226
IV. MRI Versus CT Brain Scan in Acute Stroke 231
V. Prognostic and Outcome Information Provided by Routine and Functional Brain Scan 233
VI. Vascular Imaging 237
References 241
Chapter 8: Functional Mri in Pediatric Neurobehavioral Disorders 251
I. Introduction 252
II. Normative Pediatric Functional Studies 254
III. Pediatric fMR Studies of Psychopathology 266
IV. Summary 289
References 290
Chapter 9: Structural MRI and Brain Development 297
I. Introduction 298
II. MRI Scanning and Image Analysis 300
III. Growth Curves for Different Brain Regions 305
IV. Cortical Mapping 310
V. Time-Lapse Maps of Brain Change 319
VI. Mapping Brain Growth 325
VII. Conclusion 328
Acknowledgments 329
References 329
Chapter 10: Neuroimaging and Human Genetics 337
I. Introduction 337
II. Historical Perspective 338
III. General Issues 345
IV. Heritability 352
V. Application of the Principles 356
VI. Conclusions 374
References 375
Chapter 11: Neuroreceptor Imaging in Psychiatry: Theory and Applications 397
I. Introduction 398
II. Conceptual Framework 398
III. Deriving Outcome Measures from Imaging Data 403
IV. Psychiatric Disorders 409
References 432
Index 453
Contents of Recent Volumes 468

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